Glutamate Carboxypeptidase II

Known as: Hydrolase I, Folate, Dipeptidase, N-Acetylated-alpha-Linked Acidic, N-Acetylaspartylglutamate Peptidase 
A metallocarboxypeptidase that is predominantly expressed as a membrane-bound enzyme. It catalyzes the hydrolysis of an unsubstituted, C-terminal… (More)

Topic mentions per year

Topic mentions per year

1988-2016
051019882016

Papers overview

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2003
2003
Glutamate carboxypeptidase II (EC 3.4.17.21) catalyzes the hydrolysis (Km = 0.2 microM) of the neuropeptide N… (More)
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Highly Cited
2002
Highly Cited
2002
We have identified two synthetic oligonucleotides (aptamers) that bind to prostate cancer cells,with low nanomolar affinity, via… (More)
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2002
2002
Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a membrane peptidase expressed in a number of tissues such as kidney… (More)
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2002
2002
Imaging of glutamate carboxypeptidase II (GCP II), also known as N-acetylated alpha-linked L-amino dipeptidase (NAALADase), may… (More)
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2001
2001
Inhibition of glutamate carboxypeptidase (GCP) II (EC 3.4.17.21), also termed N-acetylated alpha-linked acidic dipeptidase… (More)
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1999
1999
The enzyme glutamate carboxypeptidase II (GCP II) has been cloned from rat brain and human prostate. This enzyme, which… (More)
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Highly Cited
1999
Highly Cited
1999
We describe here a new strategy for the treatment of stroke, through the inhibition of NAALADase (N-acetylated-α-linked-acidic… (More)
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1998
1998
N-acetylated alpha-linked acidic dipeptidase (NAALADase) hydrolyzes acidic peptides, such as the abundant neuropeptide N-acetyl… (More)
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Highly Cited
1996
Highly Cited
1996
This report demonstrates that the investigational prostatic carcinoma marker known as the prostate-specific membrane antigen (PSM… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Schizophrenia has been hypothesized to be caused by a hypofunction of glutamatergic neurons. Findings of reduced… (More)
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