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glutamate carboxypeptidase II, human

Known as: PSMA antigen, Glutamate Carboxypeptidase II, Prostate-Specific Membrane Antigen 
Glutamate carboxypeptidase 2 (750 aa, ~84 kDa) is encoded by the human FOLH1 gene. This protein plays a role in the mediation of folate metabolism.
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Prostate cancer-specific positron emission tomography (pcPET) has been shown to detect sites of disease recurrence at serum… Expand
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Review
2018
Review
2018
CONTEXT 68Gallium prostate-specific membrane antigen (PSMA) ligand 68Ga-HBED-CC-PSMA (68Ga-PSMA) is a promising radiotracer for… Expand
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Review
2018
Review
2018
In this prospective survey of referring physicians, we investigated whether and how 68Ga-labeled prostate-specific membrane… Expand
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Review
2018
Review
2018
The aim of this evaluation was to identify the first indicators of efficacy for 225Ac-labeled prostate-specific membrane antigen… Expand
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Highly Cited
2014
Highly Cited
2014
PurposeSince the introduction of positron emission tomography (PET) imaging with 68Ga-PSMA-HBED-CC (=68Ga-DKFZ-PSMA-11), this… Expand
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Highly Cited
2012
Highly Cited
2012
We describe the development and clinical translation of a targeted polymeric nanoparticle (TNP) containing the chemotherapeutic… Expand
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Highly Cited
2009
Highly Cited
2009
Prostate cancer cells expressing prostate-specific membrane antigen (PSMA) have been targeted with RNA aptamer–small interfering… Expand
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Highly Cited
2006
Highly Cited
2006
Targeted uptake of therapeutic nanoparticles in a cell-, tissue-, or disease-specific manner represents a potentially powerful… Expand
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Highly Cited
2004
Highly Cited
2004
Nucleic acid ligands (aptamers) are potentially well suited for the therapeutic targeting of drug encapsulated controlled release… Expand
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Highly Cited
1996
Highly Cited
1996
OBJECTIVES To determine the expression of prostate-specific membrane antigen (PSMA) before and after androgen-deprivation therapy… Expand
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