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Glafenine

Known as: Benzoic acid, 2-((7-chloro-4-quinolinyl)amino)-, 2,3-dihydroxypropyl ester, Glaphenine, Glycerylaminophenaquine 
An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Analgesics, Non-Narcotic
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (2)

glafenic acidnicafenine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and GSH Conjugates
Glafenine (Privadol; 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolinyl) amino]benzoate) is a non-narcotic analgesic agent widely used… 
Review
2008
Review
2008
Glafenine-associated hepatic injury. Analysis of 38 cases and review of the literature.
Glafenine was associated with hepatic injury in 38 cases. The causal relationship was assessed on the basis of the temporal… 
2004
2004
Cytokine release does not improve the sensitivity and specificity of the direct popliteal lymph node assay.
Highly Cited
2003
Highly Cited
2003
Evaluation of an improved general unknown screening procedure using liquid-chromatography-electrospray-mass spectrometry by comparison with gas chromatography and high-performance liquid…
1988
1988
[Glaphenine biliary lithiasis. Identification by infrared spectrophotometry].
The authors report the case of a woman, presenting with choledocholithiasis essentially composed of glafenic acid. Identification… 
Highly Cited
1985
Highly Cited
1985
Drug induced red blood cell autoantibodies co‐developed with drug specific antibodies causing haemolytic anaemias
Summary. Four individuals with anti‐glafenine, anti‐latamoxef and anti‐teniposide antibodies were found to have an associated red… 
1984
1984
Pulmonary infiltrates with eosinophilia due to glafenine.
Pulmonary hypersensitivity in a 36-year-old man manifested by fever, abnormal lung auscultation, lung infiltrates and blood… 
1976
1976
Inhibition of prostaglandin biosynthesis by non-narcotic analgesic drugs.
The existence of a relationship between inhibition of prostaglandin biosynthesis and analgesic or anti-inflammatory activity was… 
1970
1970
Comparison of glaphenine and codeine in postoperative dental pain
A double‐blind crossover study comparing glaphenine 400 mg., a new anti‐inflammatory analgesic drug, with codeine 30 mg. was… 
1968
1968
Antagonism by fenamates and like‐acting drugs of bronchoconstriction induced by bradykinin or antigen in the guinea‐pig
1 Nine non‐steroidal anti‐inflammatory drugs were tested for antagonism of bradykinin‐induced bronchoconstriction in guinea‐pig… 
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