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Collective human food poisonings by clenbuterol residues in veal liver.
- C. Pulce, D. Lamaison, G. Keck, C. Bostvironnois, J. Nicolas, J. Descotes
- Veterinary and human toxicology
- 1 October 1991
Twenty-two patients were reported to complain of tremor, headaches, tachycardia and dizziness 1-3 h after eating veal liver. As clinical symptoms were not suggestive of an infectious cause, the… Expand
Clinical Toxicity of the Interferons
SummarySince their initial description in 1957, the interferons (IFNs) have been increasingly used to treat a wide array of diseases. Acute adverse effects, i.e. ‘flu-like’ syndromes, hypo- or… Expand
Clinical immunotoxicity of pesticides.
Because of the wide use of pesticides for domestic and industrial purposes, the evaluation of their immunotoxic effects is of major concern for public health. Despite the large amount of experimental… Expand
Contact dermatitis I. Pathophysiology of contact sensitivity.
- M. Krasteva, J. Kehren, +5 authors J. Nicolas
- European journal of dermatology : EJD
- 26 January 1999
Contact dermatitis (CD) is one of the most common skin diseases, with a great socio-economic impact. As the outermost barrier of the human body, the skin is the first to encounter chemical and… Expand
Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease.
To show the nature and magnitude of EKG anomalies subsequent to 5-fluorouracil (5FU) administration and determine whether the onset is dependent on a pre-existing cardiovascular pathological… Expand
Side Effects of Ranitidine
- T. Vial, Corinne Goubier, A. Bergeret, F. Cabrera, Jean-Claude Evreux, J. Descotes
- Drug safety
- 1 March 1991
SummaryRanitidine was first marketed in 1981; since then many patients have been treated such that much experience has been accumulated on the safety of this histamine H2-receptor antagonist in the… Expand
[Acute hepatitis due to Exolise, a Camellia sinensis-derived drug].
Clinical Toxicity of Cytokines Used As Haemopoietic Growth Factors
SummaryA number of cytokines are used as haemopoietic growth factors and this review focuses on toxicities associated with granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte… Expand
Applicability of the popliteal lymph node assay in the Brown-Norway rat.
A number of drugs and chemicals can induce autoimmune disorders. Previous studies suggested the popliteal lymph node (PLN) assay might be a suitable and reliable model to detect such compounds in the… Expand
The popliteal lymph node assay: a tool for studying the mechanisms of drug-induced autoimmune disorders.
- J. Descotes
- Toxicology letters
- 1 December 1992
Whereas it is still impossible to predict the risk for organ-specific drug-induced autoimmune disorders in animals, a large body of evidence suggests that the popliteal lymph node assay (PLNA) in… Expand