FAQ

Gilbert Disease (disorder)

Known as: Unconjugated Benign Bilirubinemia, Gilberts Disease, Meulengracht Syndrome 
A benign familial disorder, transmitted as an autosomal dominant trait. It is characterized by low-grade chronic hyperbilirubinemia with considerable… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
020406019362016

Related topics

Related topics

14 relations
Aspects of mortality statisticsAutosomal recessive inheritanceCongenital hyperbilirubinemiaCrigler Najjar syndrome, type 1
(More)

Broader (2)

CholemiaHyperbilirubinemia

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Gilbert Disease (disorder)
Autosomal recessive inheritance
prevention & control
In Blood
Hyperbilirubinemia
radiotherapeutic

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Low serum bilirubin level as an independent predictor of stroke incidence: a prospective study in Korean men and women.
BACKGROUND AND PURPOSE Bilirubin is not only a waste end-product but also an antioxidant. Bilirubin is known to be associated… (More)
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Highly Cited
2006
Highly Cited
2006
Incidence and causes of severe neonatal hyperbilirubinemia in Canada.
BACKGROUND Severe hyperbilirubinemia is the most common cause of neonatal readmission to hospital in Canada even though, in the… (More)
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Highly Cited
2003
Highly Cited
2003
Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice.
Epigallocatechin-3-gallate (EGCG), the most abundant catechin in green tea (Camellia sinensis), has shown cancer preventive… (More)
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Highly Cited
2002
Highly Cited
2002
Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels.
BACKGROUND Oxidation processes play an important role in atherogenesis. Bilirubin IXalpha is recognised as a potent antioxidant… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia.
The UDP-glucuronosyltransferase UGT1A1 plays a critical role in the detoxification of potentially neurotoxic bilirubin by… (More)
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Highly Cited
2001
Highly Cited
2001
Mechanism of indinavir-induced hyperbilirubinemia.
Indinavir is a viral protease inhibitor used for the treatment of HIV infection. Unconjugated hyperbilirubinemia develops in up… (More)
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Highly Cited
1997
Highly Cited
1997
Gilbert syndrome and glucose-6-phosphate dehydrogenase deficiency: a dose-dependent genetic interaction crucial to neonatal hyperbilirubinemia.
Severe jaundice leading to kernicterus or death in the newborn is the most devastating consequence of glucose-6-phosphate… (More)
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Highly Cited
1997
Highly Cited
1997
Severe CPT-11 toxicity in patients with Gilbert's syndrome: two case reports.
BACKGROUND CPT-11 is hydrolyzed to its active metabolite SN-38, which is mainly eliminated through conjugation by hepatic uridine… (More)
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Highly Cited
1996
Highly Cited
1996
Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome.
BACKGROUND The genetic basis of Gilbert's syndrome is ill-defined. This common mild hyperbilirubinaemia sometimes presents as an… (More)
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Highly Cited
1995
Highly Cited
1995
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.
BACKGROUND People with Gilbert's syndrome have mild, chronic unconjugated hyperbilirubinemia in the absence of liver disease or… (More)
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