Skip to search formSkip to main contentSkip to account menu

Genes, bcl-1

Known as: Gene, Cyclin D1, Gene, PRAD1, Gene, bcl-1 
The B-cell leukemia/lymphoma-1 genes, associated with various neoplasms when overexpressed. Overexpression results from the t(11;14) translocation… 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (1)

CCND1 gene
Cyclin D1Malignant lymphoma, lymphocytic, intermediate differentiation, diffuseaspects of radiation effectsphysiological aspects

Broader (1)

Proto-Oncogenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Immunohistochemical expression of cyclin D1, E2F‐1, and Ki‐67 in benign and malignant thyroid lesions
Cyclin D1 and E2F‐1 proteins are essential for the regulation of the G1/S transition through the cell cycle. Cyclin D1, a product… 
1999
1999
Proliferative fraction, bcl-1 gene translocation, and p53 mutation status as markers in mantle cell lymphoma.
The molecular genetic hallmark of mantle cell lymphomas (MCL) is the reciprocal translocation t(11;14)(q13;q32) which juxtaposes… 
1998
1998
bcl-1 gene rearrangements in mantle cell lymphoma: a comprehensive analysis of 118 cases, including B-5-fixed tissue, by polymerase chain reaction and Southern transfer analysis.
We evaluated 118 cases of mantle cell lymphoma by polymerase chain reaction (PCR) for the major translocation cluster (MTC… 
Highly Cited
1997
Highly Cited
1997
Reduction of connexin43 expression and dye‐coupling during neuronal differentiation of human NTera2/clone D1 cells
Gap junctions are plasma membrane specializations that allow direct communication among adjoining cells. We used a human… 
Highly Cited
1995
Highly Cited
1995
CD5-expressing B-cell non-Hodgkin's lymphomas with bcl-1 gene rearrangement have a relatively homogeneous immunophenotype and are associated with an overall poor prognosis.
Mantle cell lymphomas (MCLs) are typically CD5-expressing B-cell non-Hodgkin's lymphomas (NHLs) that frequently harbor the… 
1995
1995
Detection of bcl-1 gene rearrangement and B-cell clonality in mantle cell lymphoma using formalin-fixed, paraffin-embedded tissues.
Mantle cell lymphoma (MCL) has recently emerged as a distinct clinicopathologic entity with characteristic molecular genetic… 
Highly Cited
1994
Highly Cited
1994
The anaplastic variant of centrocytic lymphoma is marked by frequent rearrangements of the bcl‐1 gene and high proliferation indices
Ten cases of classic centrocytic lymphoma as defined in the Kiel classification system were investigated for their… 
1992
1992
Amplification and expression of the bcl-1 gene in human solid tumor cell lines.
The bcl-1 gene maps to chromosome 11q13 and has recently been shown to be a member of the cyclin gene family. Amplification of… 
Highly Cited
1991
Highly Cited
1991
Characterization of a candidate bcl-1 gene
The t(11;14)(q13;q32) translocation has been associated with human B-lymphocytic malignancy. Several examples of this… 
Highly Cited
1990
Highly Cited
1990
Oncogenes in multiple myeloma: point mutation of N-ras.
Alterations of ras, c-myc and bcl-1 have been described in hematologic malignancies of lymphoid origin. We investigated the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)