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Gene Products, vpr

Known as: Gene Products, vpr [Chemical/Ingredient], vpr Protein, Viral Protein R (vpr) 
Trans-acting proteins which accelerate retroviral virus replication. The vpr proteins act in trans to increase the levels of specified proteins. vpr… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2011
Highly Cited
2011
The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells
APOBEC3G (A3G) is an intrinsic antiviral factor that inhibits the replication of human immunodeficiency virus (HIV) by… 
2006
2006
Effect of R77Q, R77A and R80A changes in Vpr on HIV-1 replication and CD4 T cell depletion in human lymphoid tissue ex vivo
Background:It has been suggested that mutations of R77A and R80A in the HIV-1 viral protein R (Vpr) impair its proapoptotic… 
Review
2005
Review
2005
HIV-1 viral protein R (Vpr) & host cellular responses.
During infection of host cells by HIV-1, active host-pathogen interactions take place. The final balance between these… 
Review
2002
Review
2002
Insights into the biology of HIV-1 viral protein R.
HIV-1 viral protein R (Vpr) is a small, highly conserved accessory protein encoded by the HIV genome that serves many functions… 
2002
2002
Phosphorylation of Vpr regulates HIV type 1 nuclear import and macrophage infection.
Viral protein R (Vpr) of human immunodeficiency virus type 1 (HIV-1) is a small accessory protein that regulates nuclear import… 
2000
2000
Interactions of the C-terminus of viral protein R with nucleic acids are modulated by its N-terminus.
The basic viral protein R (Vpr) performs several functions during the human immunodeficiency virus HIV-1 retroviral cycle… 
Review
1999
Review
1999
Viral protein R of HIV‐1
Viral protein R (Vpr) of HIV‐1 belongs to a class of so called ‘accessory’ proteins, originally thought to be dispensable for… 
Highly Cited
1998
Highly Cited
1998
Arginine residues in the C-terminus of HIV-1 Vpr are important for nuclear localization and cell cycle arrest.
HIV-1 viral protein R (Vpr) is predominantly localized to the nucleus and plays an important role for viral preintegration… 
Review
1997
Review
1997
HIV‐1 viral protein R (Vpr) regulates viral replication and cellular proliferation in T cells and monocytoid cells in vitro
Among the putative accessory genes of HIV‐1, the 96‐amino‐acid virion‐associated vpr gene product has been described to have… 
Highly Cited
1996
Highly Cited
1996
A conserved LXXLF sequence is the major determinant in p6gag required for the incorporation of human immunodeficiency virus type 1 Vpr
The vpr gene product of human immunodeficiency virus type (HIV-1) is a virion-associated regulatory protein. A transferable… 
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