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Gene Dosage

Known as: Dosage, Gene, Numbers, Gene Copy, Number, Gene Copy 
The number of copies of a given gene present in the cell of an organism. An increase in gene dosage (by GENE DUPLICATION for example) can result in… 
National Institutes of Health

Related topics

Related topics

7 relations
DNA Copy Number VariationsGene AmplificationGene Dosage Compensation mechanismGene Duplication

Broader (1)

Genome

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
EGFR protein expression and gene amplification in squamous intraepithelial lesions and squamous cell carcinomas of the cervix.
The purpose of this study was to evaluate the protein expression and gene amplification of epithelial growth factor receptor… 
2012
2012
Analysis of HER-3, insulin growth factor-1, nuclear factor-kB and epidermal growth factor receptor gene copy number in the prediction of clinical outcome for K-RAS wild-type colorectal cancer…
BACKGROUND A large proportion of colorectal cancer patients does not benefit from the use of anti-epidermal growth factor… 
2012
2012
EGFR and KRAS mutations and altered c-Met gene copy numbers in primary non-small cell lung cancer and associated stage N2 lymph node-metastasis.
2012
2012
Confirmation of C4 gene copy number variation and the association with systemic lupus erythematosus in Chinese Han population
The distribution of complement component 4 (C4) gene copy number (GCN) has been validated in European populations. Meanwhile, C4… 
2011
2011
Standardisation of EGFR FISH in colorectal cancer: results of an international interlaboratory reproducibility ring study
Aims Epidermal growth factor receptor (EGFR) gene copy number evaluated by fluorescence in situ hybridisation (FISH) can… 
2011
2011
Diversity in Copy Number and Structure of a Silkworm Morphogenetic Gene as a Result of Domestication
The carotenoid-binding protein (CBP) of the domesticated silkworm, Bombyx mori, a major determinant of cocoon color, is likely to… 
2007
2007
Protein‐free transfection of CHO host cells with an IgG‐fusion protein: Selection and characterization of stable high producers and comparison to conventionally transfected clones
In order to improve the current techniques of cell cultivation in the absence of serum, we have developed a protein‐free… 
2006
2006
Analysis of aneusomy level and HER-2 gene copy number and their effect on amplification rate in breast cancer specimens read as 2+ in immunohistochemical analysis.
2000
2000
Cloning of a horn fly cDNA, HialphaE7, encoding an esterase whose transcript concentration is elevated in diazinon-resistant flies.
Highly Cited
1987
Highly Cited
1987
Expression of cell-associated and secreted forms of herpes simplex virus type 1 glycoprotein gB in mammalian cells
The gene for glycoprotein gB1 of herpes simplex virus type 1 strain Patton was expressed in stable Chinese hamster ovary cell… 
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