Gene Amplification

Known as: Amplification, Gene, natural gene amplification 
A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Aurora kinases, a family of serine/threonine kinases, consisting of Aurora A (AURKA), Aurora B (AURKB) and Aurora C (AURKC), are… (More)
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Highly Cited
2010
Highly Cited
2010
The herbicide glyphosate became widely used in the United States and other parts of the world after the commercialization of… (More)
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Highly Cited
2006
Highly Cited
2006
Overexpression of epidermal growth factor receptor (EGFR) is observed in many cancers, sometimes accompanied by gene… (More)
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Highly Cited
2001
Highly Cited
2001
PURPOSE This phase II study evaluated weekly trastuzumab and paclitaxel therapy in women with HER2-normal and HER2-overexpressing… (More)
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Highly Cited
2000
Highly Cited
2000
The 2-phenylaminopyrimidine derivative STI571 has been shown to selectively inhibit the tyrosine kinase domain of the oncogenic… (More)
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Highly Cited
1993
Highly Cited
1993
Cyclins are prime cell cycle regulators and are central to the control of major check points in eukaryotic cells. The aberrant… (More)
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Highly Cited
1992
Highly Cited
1992
Loss of cell cycle control and acquisition of chromosomal rearrangements such as gene amplification often occur during tumor… (More)
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Highly Cited
1991
Highly Cited
1991
We have developed a new expression vector which allows efficient selection for transfectants that express foreign genes at high… (More)
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Review
1991
Review
1991
INTRODUCTION ..................................................................................... 417 A Leishmania Primer… (More)
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