Gene Dosage Compensation mechanism

Known as: Compensation, Dosage (Genetics), Dosage Compensation, Genetic, dosage compensation 
Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
05010019512017

Papers overview

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Highly Cited
2011
Highly Cited
2011
For most human complex diseases and traits, SNPs identified by genome-wide association studies (GWAS) explain only a small… (More)
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Highly Cited
2010
Highly Cited
2010
Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome yet their potential involvement in human… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND In animals with heteromorphic sex chromosomes, dosage compensation of sex-chromosome genes is thought to be critical… (More)
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Highly Cited
2007
Highly Cited
2007
The contrasting dose of sex chromosomes in males and females potentially introduces a large-scale imbalance in levels of gene… (More)
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Highly Cited
2006
Highly Cited
2006
Monosomy of the X chromosome owing to divergence between the sex chromosomes leads to dosage compensation mechanisms to restore… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Drosophila melanogaster females have two X chromosomes and two autosome sets (XX;AA), while males have a single X… (More)
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Highly Cited
1999
Highly Cited
1999
The multisubunit MSL dosage compensation complex binds to hundreds of sites along the Drosophila single male X chromosome… (More)
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Highly Cited
1997
Highly Cited
1997
Dosage compensation is a regulatory process that insures that males and females have equal amounts of X-chromosome gene products… (More)
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Highly Cited
1997
Highly Cited
1997
The Drosophila roX1 gene is X-linked and produces RNAs that are male-specific, somatic, and preferentially expressed in the… (More)
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Highly Cited
1995
Highly Cited
1995
Male-specific lethal-2 (msl-2) is a RING finger protein that is required for X chromosome dosage compensation in Drosophila males… (More)
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