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Gene Dosage Compensation mechanism

Known as: Compensation, Dosage (Genetics), Dosage Compensation, Genetic, dosage compensation 
Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Gene Dosageaspects of radiation effectsphysiological aspects

Narrower (1)

dosage compensation complex assembly

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Genetic compensation: A phenomenon in search of mechanisms
Several recent studies in a number of model systems including zebrafish, Arabidopsis, and mouse have revealed phenotypic… Expand
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Highly Cited
2015
Highly Cited
2015
Condensin-Driven Remodeling of X-Chromosome Topology during Dosage Compensation
The three-dimensional organization of a genome plays a critical role in regulating gene expression, yet little is known about the… Expand
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Highly Cited
2011
Highly Cited
2011
GCTA: a tool for genome-wide complex trait analysis.
For most human complex diseases and traits, SNPs identified by genome-wide association studies (GWAS) explain only a small… Expand
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Highly Cited
2010
Highly Cited
2010
Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome yet their potential involvement in human… Expand
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Highly Cited
2007
Highly Cited
2007
Dosage compensation is less effective in birds than in mammals
BACKGROUND In animals with heteromorphic sex chromosomes, dosage compensation of sex-chromosome genes is thought to be critical… Expand
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Highly Cited
2006
Highly Cited
2006
Dosage compensation of the active X chromosome in mammals
Monosomy of the X chromosome owing to divergence between the sex chromosomes leads to dosage compensation mechanisms to restore… Expand
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Highly Cited
2006
Highly Cited
2006
Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila.
Dosage compensation in Drosophila is dependent on MSL proteins and involves hypertranscription of the male X chromosome, which… Expand
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Highly Cited
2000
Highly Cited
2000
Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila.
Dosage compensation in Drosophila involves a 2-fold increase in transcription from the single male X relative to the two female X… Expand
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Highly Cited
1997
Highly Cited
1997
Xist-deficient mice are defective in dosage compensation but not spermatogenesis.
The X-linked Xist gene encodes a large untranslated RNA that has been implicated in mammalian dosage compensation and in… Expand
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Review
1996
Review
1996
The evolution of chromosomal sex determination and dosage compensation
In many species, sex is determined by a system based on X and Y chromosomes, the latter having lost much of their genetic… Expand
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