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To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self… Expand ABSTRACT Lipid based‐formulations can enhance the bioavailability of poorly water‐soluble lipophilic drugs through enhanced… Expand PurposeMethotrexate (MTX), a potent anticancer drug, shows low oral bioavailability due to its low aqueous solubility and… Expand In this present study, the secretory transport of P-gp substrates, rhodamine 123 and digoxin, was evaluated using a Caco-2/HT29… Expand BACKGROUND
Curcumin has a wide range of pharmacological activities including antioxidant, anti-inflammatory, antidiabetic… Expand Hybrid lipid-polymer particles are gaining increasing interest to be applied as drug delivery systems due to their greater… Expand Poor water-solubility is becoming the leading hurdle for novel drug molecules to reach the market. Enhancing the surface-to… Expand Recently, self-emulsifying drug delivery systems (SEDDS) have been developed as a method to deliver lipophilic drugs. Gelucire… Expand Theophylline extended-release spheres were prepared by extrusion-spheronization of matrix granulations previously obtained by… Expand Abstract— Release of D&C Yellow No. 10 and anhydrous theophylline have been determined from a thermosoftening, hydrophilic matrix… Expand