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Ganglioside Biosynthesis Pathway

Known as: ganglioside biosynthetic process, ganglioside formation, ganglioside synthesis 
The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more… 
National Institutes of Health

Related topics

Related topics

2 relations
B4GALNT1 wt AlleleBeta-1,4 N-Acetylgalactosaminyltransferase 1, Human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson’s disease
Reduced expression of GM1 and other major brain gangliosides GD1a, GD1b and GT1b have been reported in Parkinson’s disease (PD… 
Highly Cited
2016
Highly Cited
2016
Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation
ABSTRACT Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with… 
Highly Cited
2005
Highly Cited
2005
Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions.
Gangliosides, which are sialylated glycosphingolipids, are the major class of glycoconjugates on neurons and carry the majority… 
Highly Cited
2004
Highly Cited
2004
The receptor and transporter for internalization of Clostridium botulinum type C progenitor toxin into HT-29 cells.
Highly Cited
2003
Highly Cited
2003
Gangliosides are receptors for murine polyoma virus and SV40
Polyoma virus (Py) and simian virus 40 (SV40) travel from the plasma membrane to the endoplasmic reticulum (ER) from where they… 
Highly Cited
2000
Highly Cited
2000
Glycosylation effect on membrane domain (GEM) involved in cell adhesion and motility: a preliminary note on functional alpha3, alpha5-CD82 glycosylation complex in ldlD 14 cells.
Laminin (LN)- or fibronectin (FN)-dependent adhesion in Krieger's ldlD 14 (D14) cells is enhanced significantly in the presence… 
Highly Cited
1996
Highly Cited
1996
Ganglioside Synthesis during the Development of Neuronal Polarity
Changes in the levels and types of gangliosides occur during neuronal differentiation and development, but no studies have… 
Highly Cited
1990
Highly Cited
1990
Uncoupling of ganglioside biosynthesis by Brefeldin A.
We have studied the effect of Brefeldin A (BFA), an antiviral antibiotic, on glycosphingolipid metabolism in primary cultured… 
Highly Cited
1986
Highly Cited
1986
GD2 ganglioside biosynthesis is a distinct biochemical event in human melanoma tumor progression
Highly Cited
1983
Highly Cited
1983
Tunicamycin inhibits ganglioside biosynthesis in rat liver Golgi apparatus by blocking sugar nucleotide transport across the membrane vesicles.
The synthesis of ganglioside GM1 in intact rat liver Golgi-derived vesicles is stimulated by phosphatidylglycerol as much (about… 
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