Beta-1,4 N-Acetylgalactosaminyltransferase 1, Human

Known as: GD2 Synthase, GM2 Synthase, GD2 Synthase, GalNAc-T 
Beta-1,4 N-acetylgalactosaminyltransferase 1 (533 aa, ~59 kDa) is encoded by the human B4GALNT1 gene. This protein is involved in ganglioside… (More)
National Institutes of Health

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Topic mentions per year

1984-2012
02419842012

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2006
2006
Complex glycolipid synthesis is catalyzed by different glycosyltransferases resident of the Golgi complex. Most of them are type… (More)
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2006
2006
O-repeating unit biosynthesis is the first committed step in lipopolysaccharide (LPS) biosynthesis in a variety of gram-negative… (More)
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2005
2005
Knock-out (KO) mice lacking gangliotetraose gangliosides attributable to disruption of the gene for GM2/GD2 synthase [GalNAcT… (More)
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2005
2005
Glycans containing the GalNAcbeta1-4GlcNAc (LacdiNAc or LDN) motif are expressed by many invertebrates, but this motif also… (More)
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2003
2003
PURPOSE Minimal residual disease (MRD) is one of the final hurdles to cancer cure. Because therapy (myeloablation, immunotherapy… (More)
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2002
2002
Three key regulatory enzymes in ganglioside biosynthesis, sialyltransferase I (ST1), sialyltransferase II (ST2), and N… (More)
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Highly Cited
1999
Highly Cited
1999
Gangliosides are a family of sialic acid-containing glycosphingolipids highly enriched in the mammalian nervous system. Although… (More)
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1995
1995
The amino acid sequence deduced from the cloned human cDNA of beta-1,4-N-acetylgalactosaminyltransferase (GalNAc-T; EC 2.4.1.92… (More)
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1995
1995
Treatment of the human promyelocytic leukemia cell line HL-60 with antisense oligodeoxynucleotides to UDP-N-acetylgalactosamine… (More)
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1992
1992
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids expressed in some normal tissues such as brain and in… (More)
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