FAQ

Galectin 3

Known as: Antigen, Macrophage-2, L-34, Mac-2 Antigen 
A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ… (More)
National Institutes of Health

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Topic mentions per year

1984-2017
010020019842017

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In BloodLGALS3 geneProcess of secretionadministration & dosage
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LGALS3 protein, human

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Galectin 3
physiological aspects
agonists
chemical synthesis
LGALS3 protein, human
standards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Role of Galectin-3 in Obesity and Impaired Glucose Homeostasis
Galectin-3 is an important modulator of several biological functions. It has been implicated in numerous disease conditions… (More)
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Highly Cited
2008
Highly Cited
2008
Regulation of alternative macrophage activation by galectin-3.
Alternative macrophage activation is implicated in diverse disease pathologies such as asthma, organ fibrosis, and granulomatous… (More)
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Highly Cited
2006
Highly Cited
2006
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death.
Galectins are a family of mammalian beta-galactoside-binding proteins that positively and negatively regulate T cell death… (More)
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Highly Cited
2004
Highly Cited
2004
Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction.
BACKGROUND Inflammatory mechanisms have been proposed to be important in heart failure (HF), and cytokines have been implicated… (More)
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Highly Cited
2003
Highly Cited
2003
Critical role of galectin-3 in phagocytosis by macrophages.
Galectin-3 is a member of a large family of animal lectins. This protein is expressed abundantly by macrophages, but its function… (More)
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Highly Cited
2000
Highly Cited
2000
Galectin-3 induces endothelial cell morphogenesis and angiogenesis.
Increasing evidence suggests that carbohydrate-binding proteins play an essential role in tumor growth and metastasis. However… (More)
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Highly Cited
2000
Highly Cited
2000
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.
Galectin-3 is a member of a growing family of beta-galactoside-binding animal lectins. Previous studies have demonstrated a… (More)
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Highly Cited
1997
Highly Cited
1997
Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family.
Galectin-3, a beta-galactoside-binding protein, has been shown to be involved in tumor progression and metastasis. Here, we… (More)
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Highly Cited
1996
Highly Cited
1996
Expression of galectin-3 modulates T-cell growth and apoptosis.
Galectin-3 is a member (if a large family of beta-galactoside-binding animal lectins. It has been shown that the expression of… (More)
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Highly Cited
1995
Highly Cited
1995
Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications.
Carcinoma of the thyroid gland, the most frequently diagnosed endocrine malignancy, is often associated with early regional… (More)
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