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Galectin 3
Known as:
Antigen, Macrophage-2
, L-34
, Mac-2 Antigen
Â
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A multifunctional galactin initially discovered as a macrophage antigen that binds to IMMUNOGLOBULIN E, and as 29-35-kDa lectin that binds LAMININ…Â
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1984-2017
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1984
2017
Related topics
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12 relations
In Blood
LGALS3 gene
Process of secretion
administration & dosage
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Narrower (1)
LGALS3 protein, human
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Galectin 3
physiological aspects
agonists
chemical synthesis
LGALS3 protein, human
standards characteristics
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Role of Galectin-3 in Obesity and Impaired Glucose Homeostasis
Stefano Menini
,
Carla Iacobini
,
Claudia Blasetti Fantauzzi
,
Carlo M Pesce
,
Giuseppe Pugliese
Oxidative medicine and cellular longevity
2016
Galectin-3 is an important modulator of several biological functions. It has been implicated in numerous disease conditions…Â
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Highly Cited
2008
Highly Cited
2008
Regulation of alternative macrophage activation by galectin-3.
Alison C. Mackinnon
,
Sarah L. Farnworth
,
+7 authors
Tariq Sethi
Journal of immunology
2008
Alternative macrophage activation is implicated in diverse disease pathologies such as asthma, organ fibrosis, and granulomatous…Â
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Highly Cited
2006
Highly Cited
2006
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death.
Brianna N Stillman
,
Daniel Hsu
,
+4 authors
Linda G. Baum
Journal of immunology
2006
Galectins are a family of mammalian beta-galactoside-binding proteins that positively and negatively regulate T cell death…Â
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Highly Cited
2004
Highly Cited
2004
Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction.
Umesh Chandra Sharma
,
S. Pokharel
,
+8 authors
Yigal M. Pinto
Circulation
2004
BACKGROUND Inflammatory mechanisms have been proposed to be important in heart failure (HF), and cytokines have been implicated…Â
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Highly Cited
2003
Highly Cited
2003
Critical role of galectin-3 in phagocytosis by macrophages.
Hideki Sano
,
Daniel Hsu
,
+5 authors
F. Y. Liu
The Journal of clinical investigation
2003
Galectin-3 is a member of a large family of animal lectins. This protein is expressed abundantly by macrophages, but its function…Â
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Highly Cited
2000
Highly Cited
2000
Galectin-3 induces endothelial cell morphogenesis and angiogenesis.
Pratima Nangia-Makker
,
Y. Honjo
,
+4 authors
Ayeley Raz
The American journal of pathology
2000
Increasing evidence suggests that carbohydrate-binding proteins play an essential role in tumor growth and metastasis. However…Â
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Highly Cited
2000
Highly Cited
2000
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses.
D. K. Hsu
,
R. Y. Yang
,
+4 authors
Fengyong Liu
The American journal of pathology
2000
Galectin-3 is a member of a growing family of beta-galactoside-binding animal lectins. Previous studies have demonstrated a…Â
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Highly Cited
1997
Highly Cited
1997
Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family.
Shiro Akahani
,
Pratima Nangia-Makker
,
Hideki Inohara
,
H. R. Kim
,
Ayeley Raz
Cancer research
1997
Galectin-3, a beta-galactoside-binding protein, has been shown to be involved in tumor progression and metastasis. Here, we…Â
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Highly Cited
1996
Highly Cited
1996
Expression of galectin-3 modulates T-cell growth and apoptosis.
R. Y. Yang
,
D. K. Hsu
,
Fengyong Liu
Proceedings of the National Academy of Sciences…
1996
Galectin-3 is a member (if a large family of beta-galactoside-binding animal lectins. It has been shown that the expression of…Â
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Highly Cited
1995
Highly Cited
1995
Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications.
X. C. Xu
,
A El-naggar
,
Reuben Lotan
The American journal of pathology
1995
Carcinoma of the thyroid gland, the most frequently diagnosed endocrine malignancy, is often associated with early regional…Â
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