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GW406381X
Known as:
GW406381
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Pyrazoles
Pyridazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Biomarker exposure–response relationships as the basis for rational dose selection: Lessons from a simulation exercise using a selective COX‐2 inhibitor
A. Taneja
,
S. Oosterholt
,
M. Danhof
,
O. Della Pasqua
Journal of clinical pharmacology
2016
Corpus ID: 46174567
An exposure–response model was used to characterize the pharmacokinetic‐pharmacodynamic relationship of GW406381, a COX‐2…
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2009
2009
A randomized, double-blind, placebo-controlled trial of a selective COX-2 inhibitor, GW406381, in patients with postherpetic neuralgia.
S. Shackelford
,
R. Rauck
,
S. Quessy
,
D. Blum
,
R. Hodge
,
R. Philipson
Journal of Pain
2009
Corpus ID: 36704937
2008
2008
A double‐blind, randomized, placebo‐controlled, single‐dose study of the cyclooxygenase‐2 inhibitor, GW406381, as a treatment for acute migraine
A. L. Wentz
,
T. B. Jimenez
,
Ruth Dixon
,
S. K. Aurora
,
M. Gold
European Journal of Neurology
2008
Corpus ID: 205579968
The objective of the present study was to explore the clinical efficacy and tolerability of GW406381, a cyclooxygenase‐2 (COX‐2…
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Highly Cited
2005
Highly Cited
2005
The Cyclooxygenase-2 Inhibitor GW406381X [2-(4-Ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] Is Effective in Animal Models of Neuropathic Pain and Central Sensitization
S. Bingham
,
P. Beswick
,
+20 authors
Joanne O. Wiseman
Journal of Pharmacology and Experimental…
2005
Corpus ID: 14774002
The pathogenic form of the cyclooxygenase (COX) enzyme, COX-2, is also constitutively present in the spinal cord and has been…
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2004
2004
Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.
P. Beswick
,
S. Bingham
,
+21 authors
Joanne O. Wiseman
Bioorganic & Medicinal Chemistry Letters
2004
Corpus ID: 21124544
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