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GSTA1 gene

Known as: GST, CLASS ALPHA, 1, Glutathione S-Transferase Alpha 1 Gene, glutathione S-transferase alpha 1 
This gene is involved in glutathione metabolism.
National Institutes of Health

Related topics

Related topics

3 relations
Biogenic Amine Metabolic ProcessGlutathione S-Transferase A1, Humanxenobiotic metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Population pharmacokinetic analysis of intravenous busulfan: GSTA1 genotype is not a predictive factor of initial dose in Chinese adult patients undergoing hematopoietic stem cell transplantation
This study aimed to develop a population pharmacokinetic (PPK) model to investigate the impact of GSTA1, GSTP1, and GSTM1… 
2016
2016
The relationship between GSTA1, GSTM1, GSTP1, and GSTT1 genetic polymorphisms and bladder cancer susceptibility
Background: Previous studies have investigated the relationship between GSTA1, GSTM1, GSTP1, and GSTT1 polymorphisms and bladder… 
Review
2015
Review
2015
Polymorphisms of GSTA1 contribute to elevated cancer risk: evidence from 15 studies.
PURPOSE Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens, and may be linked to carcinogenesis… 
2013
2013
MRP1 Overexpression Determines Poor Prognosis in Prospectively Treated Patients with Localized High-Risk Soft Tissue Sarcoma of Limbs and Trunk Wall: An ISG/GEIS Study
Patients with localized high-risk soft tissue sarcomas (STS) of the limbs and trunk wall still have a considerable metastatic… 
2006
2006
Human GSTA 1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells
The effect of GSTA1-1 (glutathione S-transferase Alpha 1-1) on JNK (c-Jun N-terminal kinase) activation was investigated in Caco… 
2005
2005
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate
Summary.Elevated levels of glutathione S-transferases (GSTs) are among the factors associated with an increased resistance of… 
2005
2005
Urinary GSTP1-1 excretion is markedly increased in normotensive pregnancy as well as in preeclampsia.
BACKGROUND Glutathione S-transferases (GSTs) are present in large amounts in the human kidney, where they demonstrate a specific… 
Highly Cited
2000
Highly Cited
2000
Glutathione S-transferase enzyme expression in hematopoietic cell lines implies a differential protective role for T1 and A1 isoenzymes in erythroid and for M1 in lymphoid lineages.
BACKGROUND AND OBJECTIVES Glutathione S-transferases (GSTs) are phase II metabolizing enzymes which catalyze the conjugation of… 
1998
1998
Structure-activity relationships for triphenylethylene antiestrogens on hepatic phase-I and phase-II enzyme expression.
1997
1997
Plasma glutathione S-transferase alpha 1-1 levels in patients with chronic liver disorders.
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