GSK2256098

Known as: FAK Inhibitor GSK2256098, Focal Adhesion Kinase Inhibitor GSK2256098 
A focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. FAK inhibitor GSK2256098 inhibits FAK, which… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2016
01220112016

Papers overview

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2017
2017
The introduction of targeted therapies has caused a paradigm shift in the treatment of metastatic clear cell (cc)-renal cell… (More)
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2016
2016
BACKGROUND Focal adhesion kinase (FAK) is important in cancer growth, survival, invasion, and migration. The purpose of this… (More)
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Review
2016
Review
2016
The nonreceptor protein tyrosine kinase, focal adhesion kinase (FAK, also known as PTK2), is a key mediator of signal… (More)
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2015
2015
PTEN is known to be frequently mutated in uterine cancer and also dephosphorylates FAK. Here, we examined the impact of PTEN… (More)
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2015
2015
PTEN is known to be frequently mutated in uterine cancer and also dephosphorylates FAK. Here, we examined the impact of PTEN… (More)
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2014
2014
Focal adhesion kinase (FAK) hyperactivation is common in pancreatic ductal adenocarcinoma (PDAC). A small molecule, GSK2256098… (More)
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Review
2011
Review
2011
Since its first description Focal Adhesion Kinase (FAK), a cytoplasmatic tyrosine kinase, has been implicated in the formation… (More)
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