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GRN protein, human
Known as:
granulin protein, human
, proepithelin protein, human
, PC-cell-derived growth factor, human
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Granulins (593 aa, ~64 kDa) is encoded by the human GRN gene. This protein is involved in receptor-mediated signaling.
National Institutes of Health
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Related topics
Related topics
8 relations
Extracellular Space
GRN gene
GRN wt Allele
Growth Factor
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Broader (1)
granulin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Proepithelin Stimulates Growth Plate Chondrogenesis via Nuclear Factor-κB-p65-dependent Mechanisms*
Shufang Wu
,
W. Zang
,
Xu Li
,
Hongzhi Sun
Journal of Biological Chemistry
2011
Corpus ID: 25163330
Proepithelin, a previously unrecognized growth factor in cartilage, has recently emerged as an important regulator for cartilage…
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2011
2011
Evaluation of urinary proepithelin as a potential biomarker for bladder cancer detection and prognosis in Egyptian patients.
M. Selmy
,
G. Ibrahim
,
Taher I. El Serafi
,
A. Ghobeish
Cancer Biomarkers
2011
Corpus ID: 30510629
BACKGROUND/AIM Proepithelin is a growth factor that may play a critical role in bladder cancer. Its over-expression in urine of…
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2010
2010
Progranulin (granulin/epithelin precursor) and its constituent granulin repeats repress transcription from cellular promoters
M. Hoque
,
M. Mathews
,
T. Pe’ery
Journal of Cellular Physiology
2010
Corpus ID: 39361175
Progranulin (also known as granulin/epithelin precursor, GEP) is composed of seven granulin/epithelin repeats (granulins) and…
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2010
2010
WISE‐2005: prolongation of left ventricular pre‐ejection period with 56 days head‐down bed rest in women
G. Hodges
,
L. Mattar
,
+4 authors
J. Shoemaker
Experimental Physiology
2010
Corpus ID: 206367413
This study tested the hypothesis that prolonged physical deconditioning affects the coupling of left ventricular depolarization…
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Highly Cited
2005
Highly Cited
2005
The zebrafish progranulin gene family and antisense transcripts
Benoît Cadieux
,
Babykumari P. Chitramuthu
,
David C. Baranowski
,
H. Bennett
BMC Genomics
2005
Corpus ID: 1983330
BackgroundProgranulin is an epithelial tissue growth factor (also known as proepithelin, acrogranin and PC-cell-derived growth…
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Highly Cited
1998
Highly Cited
1998
Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor).
Haidi Zhang
,
G. Serrero
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 26337824
The PC cell line is a highly tumorigenic, insulin-independent, teratoma-derived cell line isolated from the nontumorigenic…
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1997
1997
Isolation and N-terminal sequence of multiple forms of granulins in human urine.
G. Sparro
,
G. Galdenzi
,
A. Eleuteri
,
M. Angeletti
,
W. Schroeder
,
E. Fioretti
Protein Expression and Purification
1997
Corpus ID: 30086723
Three molecular forms of granulins (also known as epithelins) were isolated, for the first time, in human urine. Their N-terminal…
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Highly Cited
1994
Highly Cited
1994
Producer immunity towards the lantibiotic Pep5: identification of the immunity gene pepI and localization and functional analysis of its gene product
M. Reis
,
M. Eschbach-Bludau
,
M. I. IGLESIAS-WIND
,
T. Kupke
,
H. Sahl
Applied and Environmental Microbiology
1994
Corpus ID: 38702858
The lantibiotic Pep5 is produced by Staphylococcus epidermidis 5. Pep5 production and producer immunity are associated with the…
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1993
1993
Isolation and primary structure of the three major forms of granulin-like peptides from hematopoietic tissues of a teleost fish (Cyprinus carpio).
D. Belcourt
,
C. Lazure
,
H. Bennett
Journal of Biological Chemistry
1993
Corpus ID: 24130261
Highly Cited
1992
Highly Cited
1992
Structure and chromosomal location of the human granulin gene.
V. Bhandari
,
A. Bateman
Biochemical and Biophysical Research…
1992
Corpus ID: 28887320
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