GRN protein, human

Known as: granulin protein, human, proepithelin protein, human, PC-cell-derived growth factor, human 
Granulins (593 aa, ~64 kDa) is encoded by the human GRN gene. This protein is involved in receptor-mediated signaling.

Topic mentions per year

Topic mentions per year

1975-2017
02419752017

Papers overview

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2010
2010
AIM HDL has anti-inflammatory effects on macrophages, although the mechanism of action remains unclear. We hypothesized that HDL… (More)
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2009
2009
The growth factor proepithelin has recently emerged as an important regulator of transformation in several physiological and… (More)
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Highly Cited
2006
Highly Cited
2006
The growth factor proepithelin (also known as progranulin, acrogranin, PC-derived growth factor, or granulin-epithelin precursor… (More)
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2006
2006
Granulins are a group of highly conserved growth factors that have been described from a variety of organisms spanning the… (More)
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Highly Cited
2002
Highly Cited
2002
Increased leukocyte elastase activity in mice lacking secretory leukocyte protease inhibitor (SLPI) leads to impaired wound… (More)
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Highly Cited
2000
Highly Cited
2000
Granulins, also called epithelins, are 6-kD peptides with growth modulatory effects on a variety of cells. The granulin/epithelin… (More)
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1998
1998
Ascorbic acid is a required cofactor in the hydroxylations of lysine and proline necessary for collagen formation; its role in… (More)
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1997
1997
Three molecular forms of granulins (also known as epithelins) were isolated, for the first time, in human urine. Their N-terminal… (More)
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1993
1993
Granulins are cysteine-rich polypeptides purified from human and rat hematopoietic cells and structurally related to the… (More)
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Highly Cited
1990
Highly Cited
1990
We report the isolation and characterization of a novel class of leukocyte peptides with possible cytokine-like activities which… (More)
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