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GRN gene
Known as:
PROGRANULIN
, Granulin Gene
, GRN
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This gene is involved in cytokine-like activity.
National Institutes of Health
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Related topics
Related topics
4 relations
GRN protein, human
Signal Transduction
granulin
Narrower (1)
GRN wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Prosurvival function of the granulin‐epithelin precursor is important in tumor progression and chemoresponse
Gresin O. Pizarro
,
Xun Zhou
,
+4 authors
M. Jones
International Journal of Cancer
2007
Corpus ID: 25386407
The granulin‐epithelin precursor (GEP/PCDGF), a 68–88 kDa secreted glycoprotein, has been shown to be an important growth and…
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Review
2006
Review
2006
Recent advances in the genetics of amyotrophic lateral sclerosis and frontotemporal dementia: common pathways in neurodegenerative disease.
K. Talbot
,
O. Ansorge
Human Molecular Genetics
2006
Corpus ID: 40229692
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease classically defined by the impairment of the voluntary motor…
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Highly Cited
2004
Highly Cited
2004
PC Cell-Derived Growth Factor Mediates Tamoxifen Resistance and Promotes Tumor Growth of Human Breast Cancer Cells
Wisit Tangkeangsirisin
,
J. Hayashi
,
G. Serrero
Cancer Research
2004
Corpus ID: 178902
PC cell-derived growth factor, also known as progranulin, is an Mr 88,000 growth factor (referred as PCDGF/GP88) overexpressed in…
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Highly Cited
2002
Highly Cited
2002
The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system.
V. Baladrón
,
M. Ruiz-Hidalgo
,
E. Bonvini
,
E. Gubina
,
V. Notario
,
J. Laborda
Biochemical and Biophysical Research…
2002
Corpus ID: 34578930
Levels of dlk, an EGF-like homeotic protein, are critical for several differentiation processes. Because growth and…
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2000
2000
Suppression of copulatory behavior by intracerebroventricular infusion of antisense oligodeoxynucleotide of granulin in neonatal male rats
Masatoshi Suzuki
,
M. Bannai
,
+6 authors
Michio Takahashi
Physiology and Behavior
2000
Corpus ID: 6773492
Highly Cited
1998
Highly Cited
1998
Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor).
Haidi Zhang
,
G. Serrero
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 26337824
The PC cell line is a highly tumorigenic, insulin-independent, teratoma-derived cell line isolated from the nontumorigenic…
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Highly Cited
1994
Highly Cited
1994
Producer immunity towards the lantibiotic Pep5: identification of the immunity gene pepI and localization and functional analysis of its gene product
M. Reis
,
M. Eschbach-Bludau
,
M. I. IGLESIAS-WIND
,
T. Kupke
,
H. Sahl
Applied and Environmental Microbiology
1994
Corpus ID: 38702858
The lantibiotic Pep5 is produced by Staphylococcus epidermidis 5. Pep5 production and producer immunity are associated with the…
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1993
1993
Isolation and primary structure of the three major forms of granulin-like peptides from hematopoietic tissues of a teleost fish (Cyprinus carpio).
D. Belcourt
,
C. Lazure
,
H. Bennett
Journal of Biological Chemistry
1993
Corpus ID: 24130261
Highly Cited
1977
Highly Cited
1977
Biophysical properties of the structural components of a granulosis virus isolated from the cabbage white butterfly (Pieris brassicae).
D. Brown
,
H. Bud
,
D. Kelly
Virology
1977
Corpus ID: 29970395
Highly Cited
1975
Highly Cited
1975
Comparative studies of baculovirus granulins and polyhedrins.
M. Summers
,
G. Smith
Intervirology
1975
Corpus ID: 3307145
Granulins and polyhedrins from five baculoviruses exhibit similar chemical and physical properties. Although similarities are…
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