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GR 55562
Known as:
GR-55562
, GR55562
National Institutes of Health
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2012
2012
Serotonin (5-HT) activation of immortalized hypothalamic neuronal cells through the 5-HT1B serotonin receptor.
S. Tung
,
A. Hardy
,
M. Wheeler
,
D. Belsham
Endocrinology
2012
Corpus ID: 46671988
Serotonin [or 5-hydroxytryptamine or (5-HT)] has been implicated as a key modulator in energy homeostasis and a primary focus in…
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2010
2010
Involvement of the 5-HT(1A) receptor in the anti-immobility effects of fluvoxamine in the forced swimming test and mouse strain differences in 5-HT(1A) receptor binding.
Y. Sugimoto
,
Sachiko Furutani
,
+6 authors
J. Yamada
European Journal of Pharmacology
2010
Corpus ID: 27287671
2003
2003
Role of serotonergic mechanisms in leptin-induced suppression of milk intake in mice
J. Yamada
,
Y. Sugimoto
,
Hiroshi Hirose
,
Yoshinobu Kajiwara
Neuroscience Letters
2003
Corpus ID: 25362733
2001
2001
Selective up-regulation of 5-HT1B/1D receptors during organ culture of cerebral arteries
Natalie Løvland Hoel
,
J. Hansen-Schwartz
,
L. Edvinsson
NeuroReport
2001
Corpus ID: 1564087
5-hydroxytryptamine (5-HT) is thought to be involved in migraine headache and the pathophysiology of cerebrovascular diseases…
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2001
2001
Relaxation induced by serotonin and sumatriptan in isolated guinea pig gallbladder strips.
S. Emre-Aydıngöz
,
Ş. Erdem
,
M. Tuncer
Research in experimental medicine. Zeitschrift…
2001
Corpus ID: 24009333
The effects of 5-hydroxytryptamine (5-HT) and sumatriptan were investigated on isolated guinea pig gallbladder strips. While 0.1…
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2000
2000
Human isolated coronary artery contraction to sumatriptan characterised by the selective 5-HT1B/1D receptor antagonist GR55562.
A. Maassen VanDenBrink
,
M. Reekers
,
W. Bax
,
P. Saxena
Acta Pharmacologica et Toxicologica
2000
Corpus ID: 32718940
The antimigraine drug, sumatriptan, contracts the human coronary artery both in vivo and in vitro. Because sumatriptan has been…
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Highly Cited
1999
Highly Cited
1999
5-HT1B receptors modulate release of [3H]dopamine from rat striatal synaptosomes
H. Sarhan
,
Isabelle Cloëz-Tayarani
,
O. Massot
,
M. Fillion
,
G. Fillion
Naunyn-Schmiedeberg's Archives of Pharmacology
1999
Corpus ID: 9966404
The effect of the selective r5-HT1B agonist 3-(1,2,5,6-tetrahydro)-4-pyridil-5-pyrrolo [3,2-b] pyril-5-one (CP93,129) on the K…
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1997
1997
Differentiation between partial agonists and neutral 5-HT1B antagonists by chemical modulation of 3-[3-(N,N-dimethylamino)propyl]-4-hydroxy- N-[4-(pyridin-4-yl)phenyl]benzamide (GR-55562).
M. Lamothe
,
P. Pauwels
,
K. Belliard
,
P. Schambel
,
S. Halazy
Journal of Medicinal Chemistry
1997
Corpus ID: 21350834
The synthesis and binding affinity at cloned h5-HT1D, h5-HT1D, and h5-HT1A receptors of 3-[3-(N,N-dimethylamino)propyl]-4-hydroxy…
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Highly Cited
1996
Highly Cited
1996
Evidence for 5‐HT1‐like receptor‐mediated vasoconstriction in human pulmonary artery
M. Maclean
,
R. Clayton
,
A. Templeton
,
I. Morecroft
British Journal of Pharmacology
1996
Corpus ID: 25247944
1 The 5‐hydroxytryptamine (5‐HT) receptors mediating contraction of human isolated pulmonary artery rings were investigated…
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1995
1995
The activity of 5-HT1D receptor ligands at cloned human 5-HT1D alpha and 5-HT1D beta receptors.
D. Walsh
,
D. Beattie
,
H. Connor
European Journal of Pharmacology
1995
Corpus ID: 1617447
The present study has examined the functional activity of the 5-HT1D receptor agonist, sumatriptan, and antagonists, GR127935 (2…
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