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Comparison of the effect of endothelium on the responses to sumatriptan in rabbit isolated iliac, mesenteric and carotid arteries.
  • O. Yildiz, M. Tuncer
  • Medicine
  • Archives internationales de pharmacodynamie et de…
  • 1 September 1994
The contractions induced by the 5-hydroxytryptamine (5-HT) and 5-HT1-like receptor agonist sumatriptan in open ring segments of rabbit iliac, mesenteric and common carotid arteries were studiedExpand
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5-HT1-like receptor-mediated contraction in the human internal mammary artery.
SummaryWe wished to characterize the 5-hydroxytryptamine (5-HT) receptors mediating vasoconstriction in the human internal mammary artery (IMA). Segments of the IMA obtained from patients undergoingExpand
  • 22
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Role of prostanoids in the increased vascular responsiveness and delayed tachyphylaxis to serotonin in the kidney of spontaneously hypertensive rats.
The isolated and perfused kidney of the spontaneously hypertensive rat (SHR) exhibits an increased vascular reactivity and a delayed tachyphylaxis to serotonin (5-hydroxytryptamine) when comparedExpand
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Cyclosporin A and Cremophor-EL augment renal vascular responses to various agonists and nerve stimulation.
  • E. Yariş, M. Tuncer
  • Chemistry, Medicine
  • Archives internationales de pharmacodynamie et de…
  • 1 May 1995
The acute actions of cyclosporin A and its solvent Cremophor-EL on the rise of perfusion pressure induced by periarterial stimulation were studied in the rabbit isolated kidney. Thirty-secondExpand
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Hypertension increases the contractions to sumatriptan in the human internal mammary artery.
BACKGROUND The internal mammary artery is the graft of choice for myocardial revascularization. The tendency to spasm increases toward the distal end of the internal mammary artery, which is theExpand
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The effects of sildenafil on the functional and structural changes of ileum induced by intestinal ischemia-reperfusion in rats.
There is evidence demonstrating the protective effect of cGMP-specific phosphodiesterase type 5 (PDE5) inhibitors against ischemic injury in certain tissues. In this study, sildenafil, a potentExpand
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Amplification of responses to sumatriptan by various agonists in rabbit isolated iliac artery.
Rabbit iliac arteries (IA) were almost unresponsive to the serotonin (5-HT1-like) receptor agonist sumatriptan under control conditions, whereas this agent elicited concentration-dependentExpand
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Actions of cyclosporin A preparation and Cremophor-EL in rabbit mesenteric artery and thoracic aorta in vitro.
1. We studied the in vitro and direct effects of intravenous cyclosporin A preparation (Sandimmun) and its solvent (Cremophor-EL) on acetylcholine-induced endothelium-dependent relaxation,Expand
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The subtype of serotonin (5-HT) receptors in the rat pulmonary artery.
Serotonin (5-HT) and some alpha-agonists induced a marked contraction of ring segments of the rat pulmonary artery. Phenylephrine and 5-HT caused maximum contractions in the artery amounting to 91%Expand
  • 9
Serotonin-induced contraction of canine saphenous vein: mediation by 5-HT1 receptors.
The action of serotonin (5-HT) on alpha 1- and alpha 2-adrenoceptors was investigated on the isolated dog saphenous vein strip. Prazosin (1 X 10(-6) and 1 X 10(-5) M), an alpha 1-adrenoceptorExpand
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