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GPR56 wt Allele

Known as: BFPP, Adhesion G Protein-Coupled Receptor G1 wt Allele, GPR56 
Human ADGRG1 wild-type allele is located in the vicinity of 16q13 and is approximately 45 kb in length. This allele, which encodes adhesion G-protein… 
National Institutes of Health

Related topics

Related topics

9 relations
16q13Cell-Cell Adhesion ProcessG Protein-Coupled Receptor SignalingIntercellular Communication Process

Broader (1)

ADGRG1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Whole-transcriptome analysis of endothelial to hematopoietic stem cell transition reveals a requirement for Gpr56 in HSC generation
Using highly sensitive RNAseq to examine the whole transcriptome of enriched aortic hematopoietic stem cells and endothelial… 
Highly Cited
2014
Highly Cited
2014
Evolutionarily Dynamic Alternative Splicing of GPR56 Regulates Regional Cerebral Cortical Patterning
Development of surface folds of the human brain is controlled in sections. [Also see Perspective by Rash and Rakic] The human… 
Highly Cited
2011
Highly Cited
2011
G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination
GPR56, an orphan G protein-coupled receptor (GPCR) from the family of adhesion GPCRs, plays an indispensable role in cortical… 
Highly Cited
2010
Highly Cited
2010
GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex.
GPR56 mutations cause an autosomal recessive polymicrogyria syndrome that has distinctive radiological features combining… 
Highly Cited
2008
Highly Cited
2008
GPR56 Regulates Pial Basement Membrane Integrity and Cortical Lamination
GPR56 is a member of the family of adhesion G-protein-coupled receptors that have a large extracellular region containing a GPS… 
Highly Cited
2007
Highly Cited
2007
Disease-associated mutations affect GPR56 protein trafficking and cell surface expression.
Bilateral frontoparietal polymicrogyria (BFPP) is a congenital brain malformation resulting in irregularities on the surface of… 
Highly Cited
2006
Highly Cited
2006
GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis.
The survival and growth of tumor cells in a foreign environment is considered a rate-limiting step during metastasis. To identify… 
Highly Cited
2005
Highly Cited
2005
GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion
GPR56 (also known as TM7XN1) is a newly discovered orphan G-protein-coupled receptor (GPCR) of the secretin family that has a… 
Highly Cited
2004
Highly Cited
2004
G Protein-Coupled Receptor-Dependent Development of Human Frontal Cortex
The mammalian cerebral cortex is characterized by complex patterns of anatomical and functional areas that differ markedly… 
Highly Cited
2004
Highly Cited
2004
Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association.
By means of a variety of intracellular scaffolding proteins, a vast number of heterotrimeric G protein-coupled receptors (GPCRs… 
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