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GNRHR gene

Known as: LUTEINIZING HORMONE-RELEASING HORMONE RECEPTOR, Gonadotropin-Releasing Hormone Receptor Gene, GNRHR 
This gene plays a role in the activation of the phosphatidylinositol-calcium second messenger signal transduction pathway.
National Institutes of Health

Related topics

Related topics

8 relations
G Protein-Coupled Receptor SignalingGNRHR protein, humanGonadotropin-Releasing Hormone ReceptorKlinefelter Syndrome

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GNRHR wt Allele

Papers overview

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2006
2006
Over expression of insulin-like 3 does not prevent cryptorchidism in GNRHR or HOXA10 deficient mice.
2005
2005
Inhibition of human type i gonadotropin-releasing hormone receptor (GnRHR) function by expression of a human type II GnRHR gene fragment.
Humans possess only one functional GnRH receptor, the type I GnRH receptor (GnRHR-I). A type II GnRH receptor (GnRHR-II) gene… 
2004
2004
Species Selectivity of Nonpeptide Antagonists of the Gonadotropinreleasing Hormone Receptor Is Determined by Residues in Extracellular Loops II and III and the Amino Terminus*
Efforts to develop orally available gonadotropin-releasing hormone (GnRH) receptor antagonists have led to the discovery of… 
Highly Cited
2003
Highly Cited
2003
Multiple determinants for rapid agonist-induced internalization of a nonmammalian gonadotropin-releasing hormone receptor: a putative palmitoylation site and threonine doublet within the carboxyl…
The chicken GnRH receptor (cGnRH-R) differs from all mammalian GnRH-Rs in possessing a cytoplasmic carboxyl-terminal tail. We… 
Highly Cited
2002
Highly Cited
2002
Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells.
The hypothalamic hormone gonadotropin-releasing hormone (GnRH) stimulates the synthesis and release of the pituitary… 
2002
2002
Secondary structure of the third extracellular loop responsible for ligand selectivity of a mammalian gonadotropin-releasing hormone receptor.
The extracellular loop 3 (ECL3) of the mammalian gonadotropin-releasing hormone receptor (GnRH-R) contains an acidic amino acid… 
Highly Cited
2001
Highly Cited
2001
The porcine gonadotropin-releasing hormone receptor gene (GNRHR): genomic organization, polymorphisms, and association with the number of corpora lutea.
The interaction of gonadotropin-releasing hormone (GNRH) and its receptor (GNRHR) is critical in the endocrine regulation of… 
Highly Cited
1995
Highly Cited
1995
Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells.
The reverse transcription-polymerase chain reaction was used to evaluate the influence of gonadotropins and GnRH on GnRH receptor… 
1995
1995
Subregional mapping of the human gonadotropin-releasing hormone receptor (GnRH-R) gene to 4q between the markers D4S392 and D4S409
We have isolated nine yeast artificial chromosomes (YACs) containing the gene that encodes the human gonadotropin-releasing… 
Review
1994
Review
1994
Molecular function of the gonadotropin-releasing hormone receptor: insights from site-directed mutagenesis
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