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GNRHR gene

Known as: LUTEINIZING HORMONE-RELEASING HORMONE RECEPTOR, Gonadotropin-Releasing Hormone Receptor Gene, GNRHR 
This gene plays a role in the activation of the phosphatidylinositol-calcium second messenger signal transduction pathway.
National Institutes of Health

Papers overview

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2015
2015
Natural selection and selective breeding for genetic improvement have left detectable signatures within the genome of a species… Expand
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Highly Cited
2014
Highly Cited
2014
Molecular chaperones triage misfolded proteins via action as substrate selectors for quality control (QC) machines that fold or… Expand
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2012
2012
Background Congenital hypogonadotropic hypogonadism (HH) is a rare cause for delayed or absent puberty. These patients may… Expand
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Highly Cited
2007
Highly Cited
2007
Idiopathic hypogonadotropic hypogonadism (IHH) due to defects of gonadotropin-releasing hormone (GnRH) secretion and/or action is… Expand
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2006
2006
OBJECTIVE To determine the frequency of rare nucleotide variants in GNRHR and GPR54 in a large cohort of probands (n = 166) with… Expand
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2005
2005
Humans possess only one functional GnRH receptor, the type I GnRH receptor (GnRHR-I). A type II GnRH receptor (GnRHR-II) gene… Expand
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Highly Cited
2003
Highly Cited
2003
Hypogonadotropic hypogonadism is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and… Expand
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2000
2000
Mutation of Asp(2.61(98)) at the extracellular boundary of transmembrane helix 2 of the gonadotropin-releasing hormone (GnRH… Expand
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1996
1996
We demonstrate a critical role for Asn102 of the human gonadotropin-releasing hormone (GnRH) receptor in the binding of GnRH… Expand
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Highly Cited
1992
Highly Cited
1992
GnRH plays a pivotal role in the reproductive system, and GnRH analogs have wide therapeutic applications ranging from the… Expand
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