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GNA12 protein, human

Known as: G-Protein Alpha Subunit 12, Guanine Nucleotide Binding Protein Alpha 12, GNA12 
Encoded by human GNA12 Gene (G-Alpha 4 (G(12)) Family), 380-aa 44-kDa membrane-bound Guanine Nucleotide Binding Protein Alpha 12 is a G protein alpha… 
National Institutes of Health

Related topics

Related topics

10 relations
Environment-to-Cell CommunicationG Protein-Coupled Receptor SignalingGNA12 geneGTP Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
c-Jun Contributes to Transcriptional Control of GNA12 Expression in Prostate Cancer Cells
GNA12 is the α subunit of a heterotrimeric G protein that possesses oncogenic potential. Activated GNA12 also promotes prostate… 
2016
2016
Preeclampsia is Associated with Decreased Methylation of the GNA12 Promoter
Preeclampsia, characterized by high blood pressure, albuminuria and other systemic disorders, is a serious complication during… 
2016
2016
Abstract 2505: GNA13 induction of stemness and resistance to chemotherapy in breast and head and neck cancers
Despite advancement in cancer therapy, the ability of cancer cells to evade therapy often leads to tumor recurrence and distant… 
Highly Cited
2015
Highly Cited
2015
The metabolomics of asthma control: a promising link between genetics and disease
Short‐acting β agonists (e.g., albuterol) are the most commonly used medications for asthma, a disease that affects over 300… 
2011
2011
Genes targets identification of 5-amino-exo-3-azatricyclo[5.2.1.02,6]decane-4-one in an in vivo model of arrhythmia
The molecular mechanisms of action of 5-amino-exo-3-azatricyclo[5.2.1.02,6]decane-4-one (P11), a compound possessing strong… 
2011
2011
Expression of GNA12 and its role in oral cancer
Highly Cited
2009
Highly Cited
2009
Discovery and Scoring of Protein Interaction Subnetworks Discriminative of Late Stage Human Colon Cancer*S
We used a systems biology approach to identify and score protein interaction subnetworks whose activity patterns are… 
Highly Cited
2008
Highly Cited
2008
Gα12 regulates protein interactions within the MDCK cell tight junction and inhibits tight-junction assembly
The polarized functions of epithelia require an intact tight junction (TJ) to restrict paracellular movement and to separate… 
2005
2005
Expression of p53, pRb, Ki-67 and bcl-2 in betel quid induced oral mucosal lesions
2004
2004
Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus
AbstractHeterotrimeric guanine nucleotide binding proteins (G proteins) regulate various signals from transmembrane receptors to… 
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