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GNA12 gene

Known as: G protein subunit alpha 12, gep, GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-12 
This gene plays a role in signal transduction and cytoskeletal remodeling.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
GNA12 is the α subunit of a heterotrimeric G protein that possesses oncogenic potential. Activated GNA12 also promotes prostate… 
2016
2016
G-protein-coupled receptors (GPCRs) and their ligands function in the progression of human malignancies. Gα12 and Gα13, encoded… 
Highly Cited
2016
Highly Cited
2016
Dysregulation of PI3K and MAPK pathways promotes uncontrolled cell proliferation, apoptotic inhibition and metastasis. Individual… 
2016
2016
Preeclampsia, characterized by high blood pressure, albuminuria and other systemic disorders, is a serious complication during… 
2014
2014
Background Recent studies on the involvement of the G12 family of heterotrimeric G proteins (Gα12 and Gα13, the products of the… 
Highly Cited
2012
Highly Cited
2012
With the recent success of genome-wide association studies (GWAS), a wealth of association data has been accomplished for more… 
2008
2008
1 There are two types of familial hyperaldosteronism (FH): FH‐I and FH‐II. FH‐I is caused by a hybrid CYP11B1/CYP11B2 gene… 
2008
2008
Abstract The heterotrimeric G-protein pathway controls numerous cellular processes, including proliferation, differentiation… 
Highly Cited
1988
Highly Cited
1988
A variety of genes have been identified that specify the synthesis of the components of guanine nucleotide-binding proteins (G…