Skip to search formSkip to main contentSkip to account menu

GNA12 gene

Known as: G protein subunit alpha 12, gep, GUANINE NUCLEOTIDE-BINDING PROTEIN, ALPHA-12 
This gene plays a role in signal transduction and cytoskeletal remodeling.
National Institutes of Health

Related topics

Related topics

5 relations
Environment-to-Cell CommunicationG Protein-Coupled Receptor SignalingGNA12 protein, humanGTP Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
c-Jun Contributes to Transcriptional Control of GNA12 Expression in Prostate Cancer Cells
GNA12 is the α subunit of a heterotrimeric G protein that possesses oncogenic potential. Activated GNA12 also promotes prostate… 
2016
2016
GEP oncogene promotes cell proliferation through YAP activation in ovarian cancer
G-protein-coupled receptors (GPCRs) and their ligands function in the progression of human malignancies. Gα12 and Gα13, encoded… 
Highly Cited
2016
Highly Cited
2016
miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer
Dysregulation of PI3K and MAPK pathways promotes uncontrolled cell proliferation, apoptotic inhibition and metastasis. Individual… 
2016
2016
Preeclampsia is Associated with Decreased Methylation of the GNA12 Promoter
Preeclampsia, characterized by high blood pressure, albuminuria and other systemic disorders, is a serious complication during… 
2014
2014
Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and −8, and matrix metalloproteinase-2
Background Recent studies on the involvement of the G12 family of heterotrimeric G proteins (Gα12 and Gα13, the products of the… 
Highly Cited
2012
Highly Cited
2012
Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia
With the recent success of genome-wide association studies (GWAS), a wealth of association data has been accomplished for more… 
Highly Cited
2009
Highly Cited
2009
Gene expression in human oral squamous cell carcinoma is influenced by risk factor exposure.
2008
2008
EXAMINATION OF CHROMOSOME 7p22 CANDIDATE GENES RBaK, PMS2 AND GNA12 IN FAMILIAL HYPERALDOSTERONISM TYPE II
1 There are two types of familial hyperaldosteronism (FH): FH‐I and FH‐II. FH‐I is caused by a hybrid CYP11B1/CYP11B2 gene… 
2008
2008
RGS22, A Novel Testis-Specific Regulator of G-protein Signaling Involved in Human and Mouse Spermiogenesis along with GNA12/13 Subunits1
Abstract The heterotrimeric G-protein pathway controls numerous cellular processes, including proliferation, differentiation… 
Highly Cited
1988
Highly Cited
1988
Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.
A variety of genes have been identified that specify the synthesis of the components of guanine nucleotide-binding proteins (G… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)