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GLRX protein, human

Known as: Glutaredoxin, Glutaredoxin-1, GRX protein, human 
Glutaredoxin-1 (106 aa, ~12 kDa) is encoded by the human GLRX gene. This protein plays a role in the reduction of glutathione conjugates.
National Institutes of Health

Papers overview

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Review
2019
Review
2019
The tripeptide glutathione (GSH) and its oxidized form glutathione disulfide (GSSG) constitute a key redox couple in cells. In… Expand
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Highly Cited
2008
Highly Cited
2008
Dynamic analysis of redox-based processes in living cells is now restricted by the lack of appropriate redox biosensors… Expand
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Highly Cited
2006
Highly Cited
2006
The transcription factor NF-κB, a central regulator of immunity, is subject to regulation by redox changes. We now report that… Expand
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Review
2005
Review
2005
Reversible posttranslational modifications on specific amino acid residues can efficiently regulate protein functions. O… Expand
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Highly Cited
2004
Highly Cited
2004
Glutaredoxins catalyze glutathione-dependent thiol disulfide oxidoreductions via a GSH-binding site and active cysteines… Expand
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Highly Cited
2004
Highly Cited
2004
Angiotensin II (AII) increases production of reactive oxygen species from NAD(P)H oxidase, a response that contributes to… Expand
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Highly Cited
2000
Highly Cited
2000
Oxidative stress broadly impacts cells, initiating regulatory pathways as well as apoptosis and necrosis. A key molecular event… Expand
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Highly Cited
1998
Highly Cited
1998
The OxyR transcription factor is sensitive to oxidation and activates the expression of antioxidant genes in response to hydrogen… Expand
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Highly Cited
1998
Highly Cited
1998
Stimulation of various cells with growth factors results in a transient increase in the intracellular concentration of H2O2 that… Expand
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Highly Cited
1976
Highly Cited
1976
  • A. Holmgren
  • Proceedings of the National Academy of Sciences…
  • 1976
  • Corpus ID: 8982853
E. coli B tsnC 7004, an E. coli B/1 mutant with normal phenotype unable to replicate phage T7 DNA [Chamberlin, M. (1974)J. Virol… Expand
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