GLRX protein, human

Known as: Glutaredoxin, Glutaredoxin-1, GRX protein, human 
Glutaredoxin-1 (106 aa, ~12 kDa) is encoded by the human GLRX gene. This protein plays a role in the reduction of glutathione conjugates.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
0102019762017

Papers overview

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Highly Cited
2008
Highly Cited
2008
  • Marcus Gutscher, Anne-Laure Pauleau, +5 authors Tobias P Dick
  • Nature Methods
  • 2008
Dynamic analysis of redox-based processes in living cells is now restricted by the lack of appropriate redox biosensors… (More)
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Highly Cited
2006
Highly Cited
2006
The transcription factor NF-kappaB, a central regulator of immunity, is subject to regulation by redox changes. We now report… (More)
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Highly Cited
2004
Highly Cited
2004
Angiotensin II (AII) increases production of reactive oxygen species from NAD(P)H oxidase, a response that contributes to… (More)
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Highly Cited
2004
Highly Cited
2004
The redox poise of the mitochondrial glutathione pool is central in the response of mitochondria to oxidative damage and redox… (More)
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Highly Cited
2003
Highly Cited
2003
Glutaredoxin (GRX) is a small dithiol protein involved in various cellular functions, including the redox regulation of certain… (More)
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Highly Cited
2002
Highly Cited
2002
Epitope-tagged glutaredoxin (GRX) was utilized to determine the role of GRX in oxidative stress-induced signaling and… (More)
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Highly Cited
2000
Highly Cited
2000
Oxidative stress broadly impacts cells, initiating regulatory pathways as well as apoptosis and necrosis. A key molecular event… (More)
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Highly Cited
1998
Highly Cited
1998
Stimulation of various cells with growth factors results in a transient increase in the intracellular concentration of H2O2 that… (More)
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Highly Cited
1998
Highly Cited
1998
The OxyR transcription factor is sensitive to oxidation and activates the expression of antioxidant genes in response to hydrogen… (More)
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Highly Cited
1976
Highly Cited
1976
  • Arne Holmgren
  • Proceedings of the National Academy of Sciences…
  • 1976
E. coli B tsnC 7004, an E. coli B/1 mutant with normal phenotype unable to replicate phage T7 DNA [Chamberlin, M. (1974)J. Virol… (More)
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