GLRX gene

Known as: Glutaredoxin (Thioltransferase) Gene, GLUTAREDOXIN, THIOLTRANSFERASE 
This gene plays a role in the reduction of glutathione-disulfides and glutathione-conjugated proteins.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
051019852017

Papers overview

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Highly Cited
2007
Highly Cited
2007
The cellular glutathione redox buffer is assumed to be part of signal transduction pathways transmitting environmental signals… (More)
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2007
2007
Glutaredoxins (GRX) are antioxidant enzymes that preferentially catalyze the reduction of protein-glutathione mixed disulfides… (More)
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2006
2006
The GSH/glutaredoxin (GRX) system is involved in the redox regulation of certain enzyme activities, and this system protects… (More)
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2006
2006
Strong evidence indicates oxidative stress in the pathogenesis of Alzheimer's disease (AD). Amyloid beta (Abeta) has been… (More)
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Highly Cited
2005
Highly Cited
2005
Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and… (More)
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Highly Cited
2003
Highly Cited
2003
Glutaredoxin (GRX) is a small dithiol protein involved in various cellular functions, including the redox regulation of certain… (More)
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2003
2003
Redox-sensing molecules such as thioredoxin (TRX) and glutaredoxin (GRX) bind to apoptosis signal-regulating kinase 1 (ASK1) and… (More)
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Highly Cited
2002
Highly Cited
2002
Epitope-tagged glutaredoxin (GRX) was utilized to determine the role of GRX in oxidative stress-induced signaling and… (More)
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Highly Cited
1998
Highly Cited
1998
Glutaredoxins are small heat-stable proteins that act as glutathione-dependent disulfide oxidoreductases. Two genes, designated… (More)
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1997
1997
Previous studies have suggested that the two conserved cysteines of the HIV-1 protease may be involved in regulating protease… (More)
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