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GLMN protein, human

Known as: FKBP-Associated Protein, FK506-Binding Protein-Associated Protein, FK506-Binding Protein-Associated Protein 48 kDa 
Encoded by human GLMN Gene, two alternative isoforms of ubiquitous monomeric Glomulin interact with immunophilins FKBP59, FKBPP52, and FKBP12 that… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Adaptor Proteins, Signal TransducingCarrier Proteins
GLMN geneGLMN wt AlleleSignal TransductionSignaling Pathway Gene

Papers overview

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2013
2013
Rapidly reversible manipulation of molecular activity with dual chemical dimerizers.
The rapid, inducible, reversible modulation of molecular activities by dual CID systems. Rapamycin (Rapa) treatment induces… 
Highly Cited
2012
Highly Cited
2012
Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface.
Highly Cited
2009
Highly Cited
2009
Induced Dimerization of the Amyloid Precursor Protein Leads to Decreased Amyloid-β Protein Production*
The amyloid precursor protein (APP) plays a central role in Alzheimer disease (AD) pathogenesis because sequential cleavages by… 
2007
2007
Genetically encoded molecules for inducibly inactivating CaV channels.
Voltage-gated Ca2+ (Ca(V)) channels are central to the biology of excitable cells, and therefore regulating their activity has… 
Review
2005
Review
2005
Update on the molecular genetics of vascular anomalies.
Genetic factors play a critical role in the pathogenesis of vascular anomalies. Significant advances have been made in recent… 
2004
2004
Glomulin is predominantly expressed in vascular smooth muscle cells in the embryonic and adult mouse.
Highly Cited
2003
Highly Cited
2003
Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis
Cul1, a member of the cullin ubiquitin ligase family, forms a multiprotein complex known as SCF and plays an essential role in… 
Highly Cited
2002
Highly Cited
2002
tBID Homooligomerizes in the Mitochondrial Membrane to Induce Apoptosis*
Activation of the tumor necrosis factor R1/Fas receptor results in the cleavage of cytosolic BID to truncated tBID. tBID… 
Highly Cited
2000
Highly Cited
2000
Investigating protein-ligand interactions with a mutant FKBP possessing a designed specificity pocket.
Using structure-based design and protein mutagenesis we have remodeled the FKBP12 ligand binding site to include a sizable… 
Highly Cited
1996
Highly Cited
1996
FAP48, a New Protein That Forms Specific Complexes with Both Immunophilins FKBP59 and FKBP12
We have identified a human gene encoding a 48-kDa protein that specifically interacts with the peptidyl prolyl isomerase FK506… 
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