GCH1 gene

Known as: GTP CYCLOHYDROLASE I, GTPCH1, DYT5a 
 
National Institutes of Health

Papers overview

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2008
2008
We performed a systematic study on the frequency of point mutations and deletions of the gene GCH1 in dopa-responsive dystonia… (More)
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2008
2008
OBJECTIVES This study sought to determine the effects of endogenous tetrahydrobiopterin (BH4) bioavailability on endothelial… (More)
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Highly Cited
2008
Highly Cited
2008
Copy number polymorphism (CNP) is ubiquitous in eukaryotic genomes, but the degree to which this reflects the action of positive… (More)
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2007
2007
OBJECTIVES To assess the effect of variations in GTP cyclohydrolase gene (GCH1) on pain sensitivity in humans. METHODS Thermal… (More)
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2007
2007
BACKGROUND A haplotype in the GTP cyclohydrolase 1 (dopa-responsive dystonia) gene (GCH1) is associated with decreased persistent… (More)
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2003
2003
Administration of amphetamine to mice evokes hyperlocomotion. Dopamine deficient (DD) mice, in which tyrosine hydroxylase (TH… (More)
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Review
2002
Review
2002
Dopa responsive dystonia (DRD) is an autosomal dominant dystonia caused by mutations in the gene GCH1 in about 50% of cases. GCH1… (More)
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2000
2000
A bacterial strain capable of growing on propachlor (2-chloro-N-isopropylacetanilide) was isolated from soil by using enrichment… (More)
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2000
2000
Analysis of the gene GCH1 in 58 patients with dystonia and a positive response to L-dopa revealed mutations in 30 individuals… (More)
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1999
1999
Dopamine-deficient mice (DA-/- ), lacking tyrosine hydroxylase (TH) in dopaminergic neurons, become hypoactive and aphagic and… (More)
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