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GTP Cyclohydrolase I

Known as: Cyclohydrolase I, GTP 
National Institutes of Health

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Related topics

2 relations
GCH1 gene

Broader (1)

GTP Cyclohydrolase

Papers overview

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2020
2020
Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina
Tetrahydrobiopterin (BH4) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its… 
2019
2019
A novel GTPCH deficiency mouse model exhibiting tetrahydrobiopterin-related metabolic disturbance and infancy-onset motor impairments.
2014
2014
Polymorphisms of nitric oxide synthase and GTP cyclohydrolase I genes in Japanese patients with medication overuse headaches
We investigated whether polymorphisms of the endothelial nitric oxide synthase (eNOS), neuronal NOS (nNOS), and GTP… 
2009
2009
Certain Progestins Prevent the Enhancing Effect of 17β-Estradiol on NO-Mediated Inhibition of Platelet Aggregation by Endothelial Cells
Objectives—Estro-progestin treatments have been associated with an increased risk of thromboembolic events in postmenopausal… 
2005
2005
Reduction of GTP cyclohydrolase I feedback regulating protein expression by hydrogen peroxide in vascular endothelial cells.
We examined the effect of H(2)O(2) on the expression of GTP cyclohydrolase I (GTPCH) feedback regulating protein (GFRP). Addition… 
2001
2001
Characterization of GTP cyclohydrolase I gene expression in the human neuroblastoma SKN‐BE(2)M17: enhanced transcription in response to cAMP is conferred by the proximal promoter
GTP cyclohydrolase I (GTPCH) gene expression was investigated in the human monoamine‐containing neuroblastoma cell line SK‐N‐BE(2… 
1999
1999
GTP Cyclohydrolase I Feedback Regulatory Protein Is Expressed in Serotonin Neurons and Regulates Tetrahydrobiopterin Biosynthesis
Abstract : Tetrahydrobiopterin, the coenzyme required for hydroxylation of phenylalanine, tyrosine, and tryptophan, regulates its… 
1999
1999
Dopa-responsive dystonia induced by a recessive GTP cyclohydrolase I mutation
Abstract. GTP cyclohydrolase I (GTPCH) catalyzes the rate-limiting step of tetrahydrobiopterin (BH4) biosynthesis. GTPCH has been… 
1993
1993
Localization of GTP cyclohydrolase I (GTPCH) mRNA in the rat brain by in situ hybridization.
GTP cyclohydrolase I (GTPCH) is the first and rate-limiting enzyme in the tetrahydrobiopterin (BH4) biosynthetic pathway. BH4 is… 
1993
1993
Expression of GTP cyclohydrolase I (GTPCH) mRNA in the rat: tissue distribution and effect of reserpine.
Disruption of vesicular monoamine storage by reserpine results in a marked depletion of monoamines in the central and peripheral… 
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