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GTP Cyclohydrolase I
Known as:
Cyclohydrolase I, GTP
National Institutes of Health
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Related topics
Related topics
2 relations
GCH1 gene
Broader (1)
GTP Cyclohydrolase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Tetrahydrobiopterin Plays a Functionally Significant Role in Lipogenesis in the Oleaginous Fungus Mortierella alpina
Hongchao Wang
,
Chen Zhang
,
+5 authors
Wei Chen
Frontiers in Microbiology
2020
Corpus ID: 211190251
Tetrahydrobiopterin (BH4) is well-known as a cofactor of phenylalanine hydroxylase (PAH) and nitric oxide synthase (NOS), but its…
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2019
2019
A novel GTPCH deficiency mouse model exhibiting tetrahydrobiopterin-related metabolic disturbance and infancy-onset motor impairments.
Xiaoling Jiang
,
Huazhen Liu
,
+15 authors
Li Liu
Metabolism: clinical and experimental
2019
Corpus ID: 73429218
2014
2014
Polymorphisms of nitric oxide synthase and GTP cyclohydrolase I genes in Japanese patients with medication overuse headaches
M. Ishii
,
Mirei Yahara
,
H. Katoh
,
M. Kawamura
,
S. Shimizu
2014
Corpus ID: 4799598
We investigated whether polymorphisms of the endothelial nitric oxide synthase (eNOS), neuronal NOS (nNOS), and GTP…
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2009
2009
Certain Progestins Prevent the Enhancing Effect of 17β-Estradiol on NO-Mediated Inhibition of Platelet Aggregation by Endothelial Cells
Murielle Zerr-Fouineau
,
M. Jourdain
,
Caroline Boesch
,
M. Hecker
,
C. Bronner
,
V. Schini-Kerth
Arteriosclerosis, thrombosis, and vascular…
2009
Corpus ID: 2612427
Objectives—Estro-progestin treatments have been associated with an increased risk of thromboembolic events in postmenopausal…
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2005
2005
Reduction of GTP cyclohydrolase I feedback regulating protein expression by hydrogen peroxide in vascular endothelial cells.
M. Ishii
,
S. Shimizu
,
+5 authors
Y. Kiuchi
Journal of pharmacological sciences
2005
Corpus ID: 46164271
We examined the effect of H(2)O(2) on the expression of GTP cyclohydrolase I (GTPCH) feedback regulating protein (GFRP). Addition…
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2001
2001
Characterization of GTP cyclohydrolase I gene expression in the human neuroblastoma SKN‐BE(2)M17: enhanced transcription in response to cAMP is conferred by the proximal promoter
K. Hirayama
,
M. Shimoji
,
L. Swick
,
A. Meyer
,
G. Kapatos
Journal of neurochemistry
2001
Corpus ID: 8948058
GTP cyclohydrolase I (GTPCH) gene expression was investigated in the human monoamine‐containing neuroblastoma cell line SK‐N‐BE(2…
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1999
1999
GTP Cyclohydrolase I Feedback Regulatory Protein Is Expressed in Serotonin Neurons and Regulates Tetrahydrobiopterin Biosynthesis
G. Kapatos
,
K. Hirayama
,
M. Shimoji
,
S. Milstien
Journal of neurochemistry
1999
Corpus ID: 6945640
Abstract : Tetrahydrobiopterin, the coenzyme required for hydroxylation of phenylalanine, tyrosine, and tryptophan, regulates its…
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1999
1999
Dopa-responsive dystonia induced by a recessive GTP cyclohydrolase I mutation
W. Hwu
,
P.-J. Wang
,
K. Hsiao
,
T.-R. Wang
,
Y.-W. Chiou
,
Y. Lee
Human Genetics
1999
Corpus ID: 24559469
Abstract. GTP cyclohydrolase I (GTPCH) catalyzes the rate-limiting step of tetrahydrobiopterin (BH4) biosynthesis. GTPCH has been…
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1993
1993
Localization of GTP cyclohydrolase I (GTPCH) mRNA in the rat brain by in situ hybridization.
S. Lentz
,
K. Hirayama
,
G. Kapatos
Advances in experimental medicine and biology
1993
Corpus ID: 26426160
GTP cyclohydrolase I (GTPCH) is the first and rate-limiting enzyme in the tetrahydrobiopterin (BH4) biosynthetic pathway. BH4 is…
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1993
1993
Expression of GTP cyclohydrolase I (GTPCH) mRNA in the rat: tissue distribution and effect of reserpine.
K. Hirayama
,
S. Lentz
,
G. Kapatos
Advances in experimental medicine and biology
1993
Corpus ID: 32266681
Disruption of vesicular monoamine storage by reserpine results in a marked depletion of monoamines in the central and peripheral…
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