FAQ

GTP Cyclohydrolase I

Known as: Cyclohydrolase I, GTP 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2014
01219932014

Related topics

Related topics

2 relations
GCH1 gene

Broader (1)

GTP Cyclohydrolase

Related mentions per year

Related mentions per year

1966-2018
1960198020002020
GTP Cyclohydrolase I
GTP Cyclohydrolase
GCH1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Polymorphisms of nitric oxide synthase and GTP cyclohydrolase I genes in Japanese patients with medication overuse headaches
We investigated whether polymorphisms of the endothelial nitric oxide synthase (eNOS), neuronal NOS (nNOS), and GTP… (More)
  • table 1
  • table 2
Is this relevant?
2008
2008
Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
BACKGROUND Tetrahydrobiopterin (BH4) is an essential cofactor of endothelial nitric oxide synthase (eNOS). When BH4 levels are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Certain Progestins Prevent the Enhancing Effect of 17-Estradiol on NO-Mediated Inhibition of Platelet Aggregation by Endothelial Cells
Objectives—Estro-progestin treatments have been associated with an increased risk of thromboembolic events in postmenopausal… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2005
2005
Reduction of GTP cyclohydrolase I feedback regulating protein expression by hydrogen peroxide in vascular endothelial cells.
We examined the effect of H(2)O(2) on the expression of GTP cyclohydrolase I (GTPCH) feedback regulating protein (GFRP). Addition… (More)
Is this relevant?
2001
2001
Characterization of GTP cyclohydrolase I gene expression in the human neuroblastoma SKN-BE(2)M17: enhanced transcription in response to cAMP is conferred by the proximal promoter.
GTP cyclohydrolase I (GTPCH) gene expression was investigated in the human monoamine-containing neuroblastoma cell line SK-N-BE(2… (More)
Is this relevant?
2000
2000
Identification and characterization of basal and cyclic AMP response elements in the promoter of the rat GTP cyclohydrolase I gene.
5812 base pairs of rat GTP cyclohydrolase I (GTPCH) 5'-flanking region were cloned and sequenced, and the transcription start… (More)
Is this relevant?
1999
1999
GTP cyclohydrolase I feedback regulatory protein is expressed in serotonin neurons and regulates tetrahydrobiopterin biosynthesis.
Tetrahydrobiopterin, the coenzyme required for hydroxylation of phenylalanine, tyrosine, and tryptophan, regulates its own… (More)
Is this relevant?
1999
1999
Dopa-responsive dystonia induced by a recessive GTP cyclohydrolase I mutation
GTP cyclohydrolase I (GTPCH) catalyzes the rate-limiting step of tetrahydrobiopterin (BH4) biosynthesis. GTPCH has been… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
Is this relevant?
1993
1993
Localization of GTP cyclohydrolase I (GTPCH) mRNA in the rat brain by in situ hybridization.
 
Is this relevant?
1993
1993
Expression of GTP cyclohydrolase I (GTPCH) mRNA in the rat: tissue distribution and effect of reserpine.
 
Is this relevant?