Skip to search formSkip to main contentSkip to account menu

GTP Cyclohydrolase

Known as: GTP 7,8-8,9-dihydrolase, 8-Formylhydrolase, GTP, Cyclohydrolase, GTP 
(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring… 
National Institutes of Health

Related topics

Related topics

10 relations
GCH1 geneIn BloodProcess of secretionantagonists & inhibitors

Narrower (2)

GTP Cyclohydrolase IGTP Cyclohydrolase II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Biosynthesis of pteridines. Stopped-flow kinetic analysis of GTP cyclohydrolase I.
GTP cyclohydrolase I catalyzes a mechanistically complex ring expansion affording dihydroneopterin triphosphate from GTP. The… 
2001
2001
GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.
GTP cyclohydrolase I feedback regulatory protein (GFRP) mediates the feedback inhibition of GTP cyclohydrolase I activity by (6R… 
1998
1998
The GTP cyclohydrolase I gene in Russian families with dopa-responsive dystonia.
OBJECTIVE To search for mutations in the GTP cyclohydrolase I (GCH-I) gene in a set of Russian families with dopa-responsive… 
1996
1996
Involvement of G proteins in the effect of carbachol and cholecystokinin in rat pancreatic islets.
Phospholipase C is involved in the insulinotropic effect of carbachol (CCh) and cholecystokinin octapeptide (CCK-8). The… 
Highly Cited
1995
Highly Cited
1995
SD‐3212, a new class I and IV antiarrhythmic drug: a potent inhibitor of the muscarinic acetylcholine‐receptor‐operated potassium current in guinea‐pig atrial cells
1 By use of patch‐clamp techniques, the effects of SD‐3212, a novel antiarrhythmic drug, on the calcium current (Ica), the sodium… 
Highly Cited
1991
Highly Cited
1991
CD2 antigen mediated activation of the guanine nucleotide binding proteins p21ras in human T lymphocytes.
T cell stimulation via the TCR complex (TCR/CD3 complex) results in activation of the guanine nucleotide binding proteins encoded… 
1991
1991
Low molecular weight GTP-binding proteins in human neutrophil granule membranes.
Degranulation of neutrophils involves the differential regulation of the exocytosis of at least two populations of granules. Low… 
1987
1987
Partial reassembly of active 60S ribosomal subunits from rat liver following treatment with dimethylmaleic anhydride.
Rat liver 60S ribosomal subunits were treated with dimethylmaleic anhydride, a reagent for protein amino groups, at a 1/15,000… 
Highly Cited
1984
Highly Cited
1984
Calmodulin stimulates adenylate cyclase activity and increases dopamine activation in bovine retina
Adenylate cyclase activity in bovine retina is highly responsive to Ca2+ and the endogenous Ca2+-binding protein, calmodulin (CaM… 
1979
1979
Testosterone and its precursors and metabolites enhance guanylate cyclase activity.
Both testosterone and cyclic GMP stimulate DNA synthesis. Because cyclic GMP and testosterone seem to have similar actions, the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)