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Fumarate Hydratase, Mitochondrial, human

Known as: FH, Fumarate Hydratase, Mitochondrial, EC 4.2.1.2 
Fumarate hydratase, mitochondrial (510 aa, ~55 kDa) is encoded by the human FH gene. This protein plays a role in the meditation of the citric acid… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell RespirationCitrate Cycle (TCA Cycle) PathwayCitric Acid CycleEnzyme Gene

Broader (1)

MTHFD1L gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Binding of Complement Factor H to PorB3 and NspA Enhances Resistance of Neisseria meningitidis to Anti-Factor H Binding Protein Bactericidal Activity
ABSTRACT Among 25 serogroup B Neisseria meningitidis clinical isolates, we identified four (16%) with high factor H binding… 
Highly Cited
2014
Highly Cited
2014
Small molecule-initiated light-activated semiconducting polymer dots: an integrated nanoplatform for targeted photodynamic therapy and imaging of cancer cells.
Photodynamic therapy (PDT) is a noninvasive and light-activated method for cancer treatment. Two of the vital parameters that… 
2010
2010
Rational design of HIV-1 fluorescent hydrolysis probes considering phylogenetic variation and probe performance.
Highly Cited
2009
Highly Cited
2009
CspA-Mediated Binding of Human Factor H Inhibits Complement Deposition and Confers Serum Resistance in Borrelia burgdorferi
ABSTRACT Borrelia burgdorferi has developed efficient mechanisms for evading the innate immune response during mammalian… 
Highly Cited
2004
Highly Cited
2004
Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma
Background: Overexpression of the hypoxia inducible factor 1 (HIF-1) and HIF-2 transcription factors and the consequent… 
Highly Cited
1998
Highly Cited
1998
cyk-1: a C. elegans FH gene required for a late step in embryonic cytokinesis.
A maternally expressed Caenorhabditis elegans gene called cyk-1 is required for polar body extrusion during meiosis and for a… 
1997
1997
Neonatal diagnosis of familial hypercholesterolemia in newborns born to a parent with a molecularly defined heterozygous familial hypercholesterolemia.
This study was designed to compare blood lipid levels in newborn individuals with molecularly defined heterozygous familial… 
Highly Cited
1996
Highly Cited
1996
Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication.
Viral mutations have been implicated in alteration of the biological phenotype of hepatitis B virus (HBV). We recently cloned and… 
Highly Cited
1995
Highly Cited
1995
The proline-rich P65 protein of Mycoplasma pneumoniae is a component of the Triton X-100-insoluble fraction and exhibits size polymorphism in the strains M129 and FH
Previously, we described the identification of a novel Mycoplasma pneumoniae M129 protein, named P65 because of its apparent… 
Highly Cited
1986
Highly Cited
1986
Fumarase deficiency: a new cause of mitochondrial encephalomyopathy.
We observed a deficiency of both the mitochondrial and cytosolic forms of fumarase in a male infant with mitochondrial… 
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