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Fowlpox-Sargramostim Vaccine

Known as: GM-CSF - Fowlpox, Fowlpox-Sargramostim, fowlpox-GM-CSF 
A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF… 
National Institutes of Health

Related topics

Related topics

6 relations
Cytokine Receptor ActivationGene Expression RegulationReceptors, Granulocyte-Macrophage Colony-Stimulating Factorgranulocyte

Papers overview

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Review
2019
Review
2019
Boosting Abscopal Response to Radiotherapy with Sargramostim: A Review of Data and Ongoing Studies
Drug development in oncology today routinely focuses on approaches that utilize the patients’ immune system to destroy the… 
2014
2014
Results of a randomized phase I gene therapy clinical trial of nononcolytic fowlpox viruses encoding T cell costimulatory molecules.
Oncolytic viruses have shown promise as gene delivery vehicles in the treatment of cancer; however, their efficacy may be… 
2013
2013
Digital immunohistochemistry analysis of intratumoral immune infiltrates in prostate cancer patients treated with intraprostatic/systemic PSA-TRICOM vaccine
Purpose Preclinical studies have demonstrated that intraprostatic/ intratumoral (IT) administration of vaccine in combination… 
2005
2005
Comparative studies of Avipox-GM-CSF versus recombinant GM-CSF protein as immune adjuvants with different vaccine platforms.
2005
2005
Antitumor activity of the intratumoral injection of fowlpox vectors expressing a triad of costimulatory molecules and granulocyte/macrophage colony stimulating factor in mesothelioma
Deficiency in costimulatory molecule expression has been implicated in the ability of tumors to escape immune effectors. The… 
2005
2005
Phase I study of intravesical recombinant fowlpox-GM-CSF (rF-GMCSF) and/or recombinant Fowlpox-TRICOM (rF-TRICOM) in patients with advanced bladder cancer
4755 Background: We have shown that TCC biopsies express high levels of IL10 mRNA and in preclinical models that this IL10… 
2005
2005
The Requirement ofMultimodalTherapy ( Vaccine , LocalTumor Radiation , and Reduction of Suppressor Cells ) to Eliminate EstablishedTumors
Purpose:Numerous immune-based strategies are currently beingevaluated for cancer therapy in preclinicalmodels and clinical trials… 
2004
2004
A phase I study of sequential vaccinations with recombinant Fowlpox-PSA (L155)-TRICOM (rF)alone, or in combination with recombinant vaccinia-PSA (L155)-TRICOM (rV), and the role of GM-CSF, in…
2522 Background: Vaccine strategies targeting PSA represent a novel approach in the treatment of prostate cancer. Since PSA is a… 
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