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Forkhead Box Protein L2

Known as: FOXL2, Forkhead Transcription Factor FOXL2 
Forkhead box protein L2 (376 aa, ~39 kDa) is encoded by the human FOXL2 gene. This protein plays a role in both the development and functioning of… 
National Institutes of Health

Related topics

Related topics

12 relations
ApoptosisCell Differentiation processDNA-Binding ProteinsFOXL2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
FOXL2 Is a Female Sex-Determining Gene in the Goat
Highly Cited
2009
Highly Cited
2009
Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for Mutation Screening
To date, the contribution of disrupted potentially cis-regulatory conserved non-coding sequences (CNCs) to human disease is most… 
Highly Cited
2009
Highly Cited
2009
Foxl2 functions in sex determination and histogenesis throughout mouse ovary development
BackgroundPartial loss of function of the transcription factor FOXL2 leads to premature ovarian failure in women. In animal… 
Highly Cited
2006
Highly Cited
2006
Molecular cloning and analysis of gonadal expression of Foxl2 in the medaka, Oryzias latipes.
Review
2006
Review
2006
Foxl2 function in ovarian development.
Highly Cited
2004
Highly Cited
2004
Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene.
Premature ovarian failure in a subgroup of women with blepharophimosis-ptosis-epicanthus inversus type 1 syndrome has been… 
Highly Cited
2004
Highly Cited
2004
Isolation of chicken homolog of the FOXL2 gene and comparison of its expression patterns with those of aromatase during ovarian development
Mutations in the forkhead transcription factor gene FOXL2 are involved in ovarian failure, which occurs in human BPES syndrome… 
Highly Cited
2004
Highly Cited
2004
An evolutionary and functional analysis of FoxL2 in rainbow trout gonad differentiation.
FOXL2 is a forkhead transcription factor involved in ovarian development and function. Here, we have studied the evolution and… 
Highly Cited
2003
Highly Cited
2003
Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development.
Blepharophimosis ptosis epicanthus inversus syndrome (BPES) is a human disorder caused by mutations in the forkhead transcription… 
Review
2002
Review
2002
Genes and translocations involved in POF.
Changes at a single autosomal locus and many X-linked loci have been implicated in women with gonadal dysgenesis [premature… 
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