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Folylpolyglutamate synthase

Known as: folylpoly-gamma-glutamate synthetase, folylpolyglutamate synthetase, tetrahydrofolylpolyglutamate synthase 
National Institutes of Health

Related topics

Related topics

3 relations
FPGS gene

Narrower (1)

MET7 protein, S cerevisiae

Broader (1)

peptide synthase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Methotrexate treatment of rheumatic diseases: can we do better?
2002
2002
Characterization of the folylpolyglutamate synthetase gene and polyglutamylation of folates in the protozoan parasite Leishmania.
2001
2001
Evidence of a functional requirement for a carbamoylated lysine residue in MurD, MurE and MurF synthetases as established by chemical rescue experiments.
Enzymes MurD, MurE, MurF, folylpolyglutamate synthetase and cyanophycin synthetase, which belong to the Mur synthetase… 
1999
1999
Marked variation of thymidylate synthase and folylpolyglutamate synthetase gene expression in human colorectal tumors.
Patients with advanced colorectal cancer are currently being treated with 5-fluorouracil (5-FU)-based chemotherapy. A growing… 
Highly Cited
1998
Highly Cited
1998
Structural homologies with ATP- and folate-binding enzymes in the crystal structure of folylpolyglutamate synthetase.
Folylpolyglutamate synthetase, which is responsible for the addition of a polyglutamate tail to folate and folate derivatives, is… 
1996
1996
Organization and Alternate Splicing of the Murine Folylpolyglutamate Synthetase Gene
The organization of the murine folylpolyglutamate synthetase (FPGS) gene has been determined by sequence analysis that also… 
1993
1993
Cross-resistance studies of folylpolyglutamate synthetase-deficient, methotrexate-resistant CCRF-CEM human leukemia sublines.
CCRF-CEM human leukemia sublines resistant to short-term methotrexate (MTX) exposure as a result of decreased folylpolyglutamate… 
1987
1987
Mammalian folylpoly-gamma-glutamate synthetase. 3. Specificity for folate analogues.
A variety of folate analogues were synthesized to explore the specificity of the folate binding site of hog liver… 
1987
1987
The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates.
1975
1975
The determination of folylpolyglutamate synthetase.
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