Methotrexate treatment of rheumatic diseases: can we do better?

It is very likely that methotrexate (MTX) is the best-studied drug the world has ever seen. Indeed, this statement was undoubtedly true more than 25 years ago, prior to the widespread use of MTX for any indication except those related to oncology and dermatology. Hundreds, if not thousands, of peer-reviewed publications in the medical and scientific… CONTINUE READING