Folinic Acid-Fluorouracil-Irinotecan Regimen

Known as: FOLFIRI, FOLFIRI Regimen 
An abbreviation for a chemotherapy combination used to treat advanced colorectal cancer that has spread. It is also being studied in the treatment of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
05010015019772017

Papers overview

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Highly Cited
2013
Highly Cited
2013
Colorectal cancer (CRC) is a major cause of cancer mortality. Whereas some patients respond well to therapy, others do not, and… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE Treatment for metastatic colorectal cancer (mCRC) commonly involves a fluoropyrimidine-based chemotherapy regimen such as… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE The addition of cetuximab to irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line treatment for metastatic… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE We investigated the efficacy of fluorouracil (FU), leucovorin, irinotecan, and bevacizumab (FOLFIRI + B) in a phase II… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE Panitumumab is a fully human anti-epidermal growth factor receptor (EGFR) monoclonal antibody that improves progression… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND We investigated the efficacy of cetuximab plus irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE The Gruppo Oncologico Nord Ovest (GONO) conducted a phase III study comparing fluorouracil, leucovorin, oxaliplatin, and… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE This phase III study compared the safety and efficacy of the following three different irinotecan-containing regimens in… (More)
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Highly Cited
2006
Highly Cited
2006
To compare the efficacy and toxicity of oxaliplatin (L-OHP) in combination with irinotecan (CPT-11), 5-fluorouracil (5-FU) and… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE In metastatic colorectal cancer, phase III studies have demonstrated the superiority of fluorouracil (FU) with leucovorin… (More)
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