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Folate

Known as: 2-[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid, Vitamin B-11, folates 
A cofactor for 1-carbon transfer involved with DNA synthesis.
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (1)

Folacin
Folate [Mass or Molecules/volume] in Serum or PlasmaFolate [Mass/volume] in Serum or PlasmaFolate:MCnc:Pt:Bld:QnFolate:MCnc:Pt:CSF:Qn

Broader (2)

Folic AcidVitamin B Complex

Papers overview

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Highly Cited
1989
Highly Cited
1989
Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
CEM/MTX cells, a subline of CCRF-CEM cells resistant to methotrexate (MTX) by virtue of impaired transport by the reduced folate… 
1989
1989
Folate absorption in alcoholic pigs: in vivo intestinal perfusion studies.
To determine if impaired intestinal absorption contributes to the folate deficiency observed in chronic alcoholics, we assessed… 
Highly Cited
1986
Highly Cited
1986
Transport of folate compounds in L1210 cells: kinetic evidence that folate influx proceeds via the high-affinity transport system for 5-methyltetrahydrofolate and methotrexate.
Folate is transported into L1210 mouse leukemia cells by the same system that mediates the uptake of methotrexate and reduced… 
1982
1982
Folate pentaglutamate and folate hexaglutamate mediated one-carbon metabolism.
The proposal that folate polyglutamate cofactors of different chain lengths function differently in metabolism was investigated… 
1982
1982
High performance liquid chromatography of folates: identification of poly-gamma-glutamate chain lengths of labeled and unlabeled folates.
A sensitive method is described for the identification of the polyglutamate chain lengths of labeled and unlabeled folates in… 
Highly Cited
1981
Highly Cited
1981
Hepatic folate metabolism in the chronic alcoholic monkey.
To assess the role of altered hepatic folate metabolism in the pathogenesis of the folate deficiency of chronic alcoholism, the… 
Highly Cited
1976
Highly Cited
1976
Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis.
The binding of deoxynucleoside 5'-monophosphates and various folate derivatives to Lactobacillus casei thymidylate synthetase was… 
Highly Cited
1975
Highly Cited
1975
Folate-dependent 1-carbon transfer to biogenic amines mediated by methylenetetrahydrofolate reductase
IT has been suggested that N-methylation of biogenic amines is involved in the development of certain schizophrenic disorders1,2… 
1975
1975
Purification of folate binding factor in normal umbilical cord serum.
Human umbilical cord serum was found to contain both free folate and folate complexed to a high-molecular weight factor. The… 
1975
1975
The heterogeneity and properties of folate binding proteins from chronic myelogenous leukemia cells.
Previous studies have demonstrated that some chronic myelogenous leukemia cells contain a macromolecular binding factor for folic… 
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