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Folate

Known as: 2-[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid, Vitamin B-11, folates 
A cofactor for 1-carbon transfer involved with DNA synthesis.
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (1)

Folacin
Folate [Mass or Molecules/volume] in Serum or PlasmaFolate [Mass/volume] in Serum or PlasmaFolate:MCnc:Pt:Bld:QnFolate:MCnc:Pt:CSF:Qn

Broader (2)

Folic AcidVitamin B Complex

Papers overview

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Highly Cited
1986
Highly Cited
1986
Transport of folate compounds in L1210 cells: kinetic evidence that folate influx proceeds via the high-affinity transport system for 5-methyltetrahydrofolate and methotrexate.
Folate is transported into L1210 mouse leukemia cells by the same system that mediates the uptake of methotrexate and reduced… 
1985
1985
Folate analogues as substrates of mammalian folylpolyglutamate synthetase.
The antifolate drugs methotrexate (MTX) and aminopterin (AM) have been tested as substrates for folylpolyglutamate synthetase… 
1982
1982
Hydrogen-1, carbon-13, and phosphorus-31 nuclear magnetic resonance studies of the dihydrofolate reductase-nicotinamide adenine dinucleotide phosphate-folate complex: characterization of three…
The Lactobacillus casei dihydrofolate reductase-folate-NADP+ complex is shown by 1H and 13C NMR to exist in three interconverting… 
Highly Cited
1981
Highly Cited
1981
Hepatic folate metabolism in the chronic alcoholic monkey.
To assess the role of altered hepatic folate metabolism in the pathogenesis of the folate deficiency of chronic alcoholism, the… 
1981
1981
Fluorine-19 nuclear magnetic resonance characterization of ternary complexes of folate derivatives, 5-fluorodeoxyuridylate and Lactobacillus.
Numerous biochemical techniques have been employed to characterize the covalent inhibitory ternary complex of thymidylate… 
1978
1978
Phenotype dependence in the inhibition of red cell acid phosphatase (ACP) by folates.
Red cell acid phosphatase (ACP) is shown to be inhibited by folic acid and various folates. The degree of inhibition is phenotype… 
Highly Cited
1976
Highly Cited
1976
Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis.
The binding of deoxynucleoside 5'-monophosphates and various folate derivatives to Lactobacillus casei thymidylate synthetase was… 
Highly Cited
1975
Highly Cited
1975
Folate-dependent 1-carbon transfer to biogenic amines mediated by methylenetetrahydrofolate reductase
IT has been suggested that N-methylation of biogenic amines is involved in the development of certain schizophrenic disorders1,2… 
1974
1974
Folate binding in animal plasma.
Plasma from pig, sheep, goat, cattie, horse, rabbit, dog, rat, guinea pig, and chicken was examined for the presence of specific… 
1972
1972
Folate coenzymes of Clostridium acidi-urici. The isolation of (l)-5,10-methenyltetrahydropteroyltriglutamate, its conversion to (l)-tetrahydropteroyltriglutamate and (l)-10-( 14 C…
Abstract (l-)5,10-Methenyltetrahydropteroyltriglutamic acid was isolated from Clostridium acidi-urici. The procedure yielded…