Flucytosine

Known as: 5-Fluorocystosine, Fluorcytosine, 2(1H)-Pyrimidinone, 4-amino-5-fluoro- 
A pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity. After penetration into the fungal cells, flucytosine is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
This part of the EFISG guidelines focuses on non-neutropenic adult patients. Only a few of the numerous recommendations can be… (More)
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Highly Cited
2010
Highly Cited
2010
Cryptococcosis is a global invasive mycosis associated with significant morbidity and mortality. These guidelines for its… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Cryptococcal meningitis is a major cause of human immunodeficiency virus (HIV)-associated morbidity and mortality in… (More)
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Highly Cited
2007
Highly Cited
2007
Human adipose tissue-derived mesenchymal stem cells (AT-MSC) are considered to be a promising source of autologous stem cells in… (More)
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Highly Cited
1994
Highly Cited
1994
The crystal structure has been determined at 2.8 A resolution for a chemically-trapped covalent reaction intermediate between the… (More)
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Highly Cited
1994
Highly Cited
1994
The gene encoding cytosine deaminase (CD) has been expressed in the human colorectal carcinoma cell line WiDr. Metabolism studies… (More)
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Highly Cited
1992
Highly Cited
1992
Expression of the bacterial gene for cytosine deaminase (CD; EC 3.5.4.1) in mammalian cells was evaluated as a negative selection… (More)
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Highly Cited
1990
Highly Cited
1990
OBJECTIVE To compare the efficacy of fluconazole with amphotericin B plus flucytosine in the treatment of cryptococcal meningitis… (More)
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Highly Cited
1987
Highly Cited
1987
One hundred ninety-four patients with cryptococcal meningitis were enrolled in a multicenter, prospective, randomized clinical… (More)
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Highly Cited
1979
Highly Cited
1979
We compared amphotericin B therapy for cryptococcal meningitis with a newer regimen containing both amphotericin B and… (More)
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