Fenofibrate

Known as: Procetofene, Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester, Procetofen 
A synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity. Fenofibrate is hydrolyzed in vivo to its active metabolite… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
010020019762018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Fenofibrate caused an acute, sustained plasma creatinine increase in the Fenofibrate Intervention and Event Lowering in Diabetes… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND We investigated whether combination therapy with a statin plus a fibrate, as compared with statin monotherapy, would… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE We explored whether cardiovascular disease (CVD) risk and the effects of fenofibrate differed in subjects with and… (More)
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Highly Cited
2009
Highly Cited
2009
Peroxisome proliferator-activated receptor-alpha (PPARalpha) agonists such as fenofibrate are used to treat dyslipidemia… (More)
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Highly Cited
2008
Highly Cited
2008
Angiogenesis and inflammation are central processes through which the tumor microenvironment influences tumor growth. We have… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Laser treatment for diabetic retinopathy is often associated with visual field reduction and other ocular side-effects… (More)
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Highly Cited
2007
Highly Cited
2007
The present work was aimed at formulating a SMEDDS (self-microemulsifying drug delivery system) of fenofibrate and evaluating its… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Patients with type 2 diabetes mellitus are at increased risk of cardiovascular disease, partly owing to dyslipidaemia… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES We compared vascular and metabolic responses (and adverse responses) to statin and fibrate therapies alone or in… (More)
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Highly Cited
2001
Highly Cited
2001
  • Lancet
  • 2001
BACKGROUND Atherosclerosis is the most common complication of diabetes. Correction of hyperglycaemia helps to prevent… (More)
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