Felodipine

Known as: Felodipinum, Felodipina, 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester 
A dihydropyridine calcium channel blocking agent. Felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Amorphous solid dispersions are used as a strategy to improve the bioavailability of poorly water-soluble compounds. When… (More)
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Highly Cited
2006
Highly Cited
2006
The ability of various polymers to inhibit the crystallization of amorphous felodipine was studied in amorphous molecular… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To compare the incidence of stroke and other cardiovascular events in hypertensive patients receiving a low-dose… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The efficacy of new antihypertensive drugs has been questioned. We compared the effects of conventional and newer… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Despite treatment, there is often a higher incidence of cardiovascular complications in patients with hypertension… (More)
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Review
1998
Review
1998
The novel finding that grapefruit juice can markedly augment oral drug bioavailability was based on an unexpected observation… (More)
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Highly Cited
1997
Highly Cited
1997
The increase in oral availability of felodipine and other commonly used medications when taken with grapefruit juice has been… (More)
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Highly Cited
1993
Highly Cited
1993
Grapefruit juice produces a marked and variable increase in felodipine bioavailability. The pharmacokinetics of felodipine and… (More)
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Highly Cited
1989
Highly Cited
1989
The acute hemodynamic and pharmacokinetic interactions between the vasodilating/diuretic drugs ethanol and felodipine, a 1,4… (More)
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Highly Cited
1985
Highly Cited
1985
Felodipine, a new ant (hypertensive ‘calcium antagonist’, was tested in animal experiments which specifically demonstrated its… (More)
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