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Felodipine

Known as: Felodipinum, Felodipina, 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester 
A dihydropyridine calcium channel blocking agent. Felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Amorphous solid dispersions are used as a strategy to improve the bioavailability of poorly water-soluble compounds. When… Expand
Highly Cited
2006
Highly Cited
2006
The ability of various polymers to inhibit the crystallization of amorphous felodipine was studied in amorphous molecular… Expand
Highly Cited
2006
Highly Cited
2006
PurposeThe objective of this study was to investigate thermodynamic and kinetic factors contributing to differences in the… Expand
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Highly Cited
2005
Highly Cited
2005
Objective To compare the incidence of stroke and other cardiovascular events in hypertensive patients receiving a low-dose… Expand
Highly Cited
2005
Highly Cited
2005
Solid dispersions of felodipine were formulated with HPMC and surfactants by the conventional solvent evaporation (CSE) and… Expand
Highly Cited
1999
Highly Cited
1999
BACKGROUND The efficacy of new antihypertensive drugs has been questioned. We compared the effects of conventional and newer… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Despite treatment, there is often a higher incidence of cardiovascular complications in patients with hypertension… Expand
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Review
1998
Review
1998
The novel finding that grapefruit juice can markedly augment oral drug bioavailability was based on an unexpected observation… Expand
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Highly Cited
1997
Highly Cited
1997
The increase in oral availability of felodipine and other commonly used medications when taken with grapefruit juice has been… Expand
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Highly Cited
1991
Highly Cited
1991
Six men with borderline hypertension took felodipine 5 mg with water, grapefruit juice, or orange juice. The mean felodipine… Expand