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Farnesyl Transferase Inhibitor

Known as: Farnesyl Transferase Inhibitors, Farnesyltransferase Inhibitors, FTI 
Any substance that inhibits protein farnesyltransferase, an enzyme that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a… 
National Institutes of Health

Papers overview

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2017
2017
PENERAPAN TECHNOLOGY ACCEPTANCE MODEL (TAM) PADA RADIO FREQUENCY IDENTIFICATION (RFID) DI FTI UKSW (STUDI KASUS: DOSEN FTI UKSW)
FTI UKSW saat ini sudah menerapkan teknologi RFID sebagai sistem kunci yang baru, sebelumnya sistem kunci di FTI menggunakan… 
Review
2008
Review
2008
Research on Hutchinson-Gilford progeria syndrome.
IN this issue of the Journal, I have included a summary of a workshop held in November 2007 on the topic of Hutchinson-Gilford… 
Review
2004
Review
2004
Radiation Sensitization by Inhibition of Activated Ras
Background and Purpose:Ras has been identified as a significant contributor to radiation resistance. This article reviews… 
2001
2001
The Farnesyltransferase Inhibitor L 744 , 832 Reduces Hypoxia in Tumors Expressing
Many tumors contain extensive regions of hypoxia. Because hypoxic cells are markedly more resistant to killing by radiation… 
Review
2001
Review
2001
Endocrine-Related Cancer ( 2001 ) 8 227 – 235 Farnesyl transferase inhibitors – a novel therapy for breast cancer
Inhibitors of the enzyme farnesyl protein transferase prevent a key step in the post-translational processing of the Ras protein… 
2000
2000
Antisense approaches enter the clinic.
The last decade of the twentieth century saw an explosion in the application of molecular biology toward developing pathways for… 
1999
1999
Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy.
The synthesis and evaluation of analogues of previously reported farnesyltransferase inhibitors, pyridyl benzyl ether 3 and… 
1999
1999
Clinical trials referral resource. Clinical trials with the farnesyl transferase inhibitor R115777.
1999
1999
Inhibition of DNA Synthesis by a Farnesyltransferase Inhibitor Involves Inhibition of the p 70 s 6 k Pathway *
Previously, the protein farnesyltransferase inhibitor (FTI), L-744,832, has been shown to inhibit the proliferation of a number… 
1997
1997
Syntheses and absolute structures of novel protein farnesyltransferase inhibitors, kurasoins A and B.
(70% of theory) and >90% ee, as determined by NMR analysis of the derived ( + )-MTPA ester.5) Protection of (-)-6 by TBSC1 and… 
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