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Factor Xa
Known as:
Xa, Coagulation Factor
, prothrombase
, Factor Xa [Chemical/Ingredient]
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Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of…
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National Institutes of Health
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Related topics
Related topics
16 relations
Coagulants
Process of secretion
Thromboplastin
agonists
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Narrower (5)
Factor Xa, des(1-45)-
PRT064445
dansyl-glutamyl-glycyl-arginyl chloromethyl ketone-treated factor Xa
glutamyl-glycyl-arginyl chloromethyl ketone inactivated human factor Xa
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Broader (1)
factor X
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Anticoagulant antidotes start yielding Phase III promise
Daniel Jones
Nature reviews. Drug discovery
2014
Corpus ID: 31862099
Portola's andexanet alfa and Boehringer Ingelheim's idarucizumab are both due to be filed for approval this year, with big…
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2008
2008
Hypercoagulability in rats is increased by low doses of the direct thrombin inhibitor melagatran, but is reduced by the direct Factor Xa inhibitor rivaroxaban
E. Perzborn
,
U. Buetehorn
,
E. Fischer
,
M. Harwardt
,
M. Klages
,
A. Trabandt
2008
Corpus ID: 74440494
85236 presented at the European Society of Cardiology (ESC) Congress 2008, Munich, Germany; 30 August–3 September 2008
2000
2000
Pre-Clinical Pharmacological Profile of the Novel Glycoconjugate Org 36764 with both Factor Xa and Thrombin (IIa) Inhibitory Activities
G. Vogel
,
R. V. van Amsterdam
,
T. V. Van Dinther
,
M. Tromp
,
D. Meuleman
Thrombosis and Haemostasis
2000
Corpus ID: 40912952
Summary Org 36764, is an antithrombin III (AT) and thrombin binding carbohydrate, which accelerates the inactivation of both…
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1999
1999
Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
I. Mochalkin
,
A. Tulinsky
Acta Crystallographica Section D: Biological…
1999
Corpus ID: 36165225
Most thrombin active-site inhibitors form a short antiparallel beta-strand with residues Ser214-Gly216. However, the Selectide…
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1995
1995
Improved factor Xa cleavage of fusion proteins containing maltose binding protein.
P. L. Rodriguez
,
Luis Carrasco
BioTechniques
1995
Corpus ID: 44438230
The addition of five glycine residues at a position adjacent to the factor Xa cleavage site of a MBP-2C fusion protein…
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Review
1979
Review
1979
Proteinase inhibitors in severe inflammatory processes (septic shock and experimental endotoxaemia): biochemical, pathophysiological and therapeutic aspects.
Hans Fritz
Ciba Foundation symposium
1979
Corpus ID: 19348821
Plasma levels of antithrombin III, alpha 2-macroglobulin and inter-alpha-trypsin inhibitor, as well as those of various clotting…
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1972
1972
The Effects of Salts and of Ionic Strength on the Hydrolysis of TAME (p-toluenesulfonyl-L-arginine methyl ester) by Thrombin and Thrombokinase
P. S. Roberts
,
P. B. Fleming
Thrombosis and Haemostasis
1972
Corpus ID: 41174279
Summary The effects of varying concentrations of alkali chlorides (LiCl, NaCl, KC1, RbCl and CsCl), alkaline earth chlorides…
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1966
1966
The activation of proaccelerin by bovine thrombokinase (with notes on the antithrombic activity of phenylmethyl sulfonylfluoride).
R. T. Breckenridge
,
Oscar D. Ratnoff
Blood
1966
Corpus ID: 33230880
Through the kindness of Dr. J. H. Milstone we were able to perform clotting studies with purified bovine thrombokinase…
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1964
1964
THROMBOKINASE AS PRIME ACTIVATOR OF PROTHROMBIN: HISTORICAL PERSPECTIVES AND PRESENT STATUS.
Milstone Jh
1964
Corpus ID: 163755324
1958
1958
Untersuchungen über den Tlirombokinase-Bildungstest
H. Egli
,
R. Klesper
Thrombosis and Haemostasis
1958
Corpus ID: 81600613
Zusammenfassung Der Einfluß eines Oberflächenkontaktes auf die Aktivität der im Blutserum enthaltenen, an der Bildung von…
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