Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

FYX-051

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
4-[5-(Pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile (FYX-051) is a potent inhibitor of bovine milk xanthine… Expand
  • table 1
Is this relevant?
2011
2011
As a precedent study for elucidating the mechanism of possible urinary bladder carcinogenesis due to xanthine crystals induced by… Expand
Is this relevant?
2010
2010
To clarify the toxicological aspects of FYX-051, a xanthine oxidoreductase inhibitor, which is currently being developed as a… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • table 1
Is this relevant?
2009
2009
Our previous study identified 2-[2-(2-methoxyethoxy)ethoxy]-5-[5-(2-methyl-4-pyridyl)-1H-[1,2,4] triazol-3-yl]benzonitrile (2… Expand
Is this relevant?
2009
2009
The present studies were performed to investigate the possible mechanism of marked species differences on nephropathy found in… Expand
  • table 1
  • table 1
  • figure 1
  • figure 2
  • table 2
Is this relevant?
2008
2008
Xanthine oxidoreductase (XOR) catalyzes the reaction of hypoxanthine to xanthine and of xanthine to uric acid. Inhibitors of XOR… Expand
  • figure 3
Is this relevant?
2007
2007
In humans, orally administered 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051) is excreted mainly as… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 6
  • figure 7
Is this relevant?
2006
2006
FYX-051, 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl)pyridine-2-carbonitrile, is a novel xanthine oxidoreductase inhibitor that can… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2006
2006
To determine a rat strain appropriate for carcinogenicity testing of FYX-051, a xanthine oxidoreductase inhibitor, we performed a… Expand
Is this relevant?
2005
2005
The possible mechanism of the underlying nephropathy found in the rat toxicity study of FYX-051, a xanthine oxidoreductase… Expand
Is this relevant?