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topiroxostat

Known as: 4-(5-(Pyridin-4-yl)-1h-1,2,4-triazol-3-yl)pyridine-2-carbonitrile 
 
National Institutes of Health

Papers overview

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2018
2018
We aimed to evaluate the anti‐albuminuric effects of topiroxostat in Japanese hyperuricaemic patients with diabetic nephropathy. 
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2016
2016
Topiroxostat, a xanthine oxidoreductase (XOR) inhibitor, has been shown to decrease the urinary albumin-to-creatinine ratio… Expand
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2016
2016
There are no clinical reports that have compared topiroxostat, a selective xanthine oxidase inhibitor, with allopurinol in serum… Expand
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2016
2016
Topiroxostat, a selective xanthine oxidoreductase inhibitor, is used in Japan for the treatment of hyperuricemic patients with or… Expand
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2016
2016
In Japan, although topiroxostat, a selective xanthine oxidoreductase inhibitor, has been used for the treatment of patients with… Expand
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2016
2016
ABSTRACT Proteinuria is an established risk factor for diabetic nephropathy. Recent studies indicate that some xanthine oxidase… Expand
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2016
2016
The aim of this study was to establish the rat model for evaluating hypouricemic effects by some uricosuric agents. 
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2016
2016
The aim of the present study was to reveal the effect of a xanthine oxidoreductase (XOR) inhibitor, topiroxostat (Top), compared… Expand
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Highly Cited
2014
Highly Cited
2014
AbstractBackground Topiroxostat, a selective xanthine oxidase inhibitor, shows effective reduction in the serum urate level in… Expand
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2014
2014
A QT/QTc study was conducted in compliance with ICH E14 guideline to evaluate the effects of a new xanthine oxidase inhibitor… Expand
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