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FR 900482
Known as:
3,9-Epoxy-3H-azirino(2,3-c)(1)benzazocine-5-carboxaldehyde, 8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,9,9a-hexahydro-7,9-dihydroxy-
, FR-900482
, FR900482
National Institutes of Health
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Oxazines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Development of a flexible strategy towards FR900482 and the mitomycins.
B. Trost
,
B. O’Boyle
,
W. Torres
,
M. Ameriks
Chemistry
2011
Corpus ID: 35358433
FR900482 and the mitomycins are two intriguing classes of alkaloid natural products that have analogous biological mechanisms and…
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2009
2009
Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C.
Stephen Chamberland
,
S. Grüschow
,
D. Sherman
,
Robert M. Williams
Organic Letters
2009
Corpus ID: 29388634
Beyond the identification of 3-amino-5-hydroxybenzoic acid (AHBA) and D-glucosamine as biosynthetic precursors to mitomycin C (5…
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2007
2007
Synthetic and biosynthetic studies on FR900482 and mitomycin C: an efficient and stereoselective hydroxymethylation of an advanced benzazocane intermediate.
Hidenori Namiki
,
Stephen Chamberland
,
Daniel A. Gubler
,
Robert M. Williams
Organic Letters
2007
Corpus ID: 46446021
We report a simple, efficient, and stereoselective Mukaiyama aldol approach to install the key hydroxymethyl moiety into the…
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2003
2003
Formal enantiospecific synthesis of (+)-FR900482.
M. Paleo
,
Natalia Aurrecoechea
,
K. Jung
,
H. Rapoport
Journal of Organic Chemistry
2003
Corpus ID: 33321463
The enantiospecific synthesis of FK973, and thus a formal enantiospecific synthesis of the antitumor antibiotic (+)-FR900482, is…
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2002
2002
Differential effects of FR900482 and FK317 on apoptosis, IL-2 gene expression, and induction of vascular leak syndrome.
Lois Beckerbauer
,
J. Tepe
,
Rebecca A Eastman
,
P. Mixter
,
Robert M. Williams
,
R. Reeves
Chemistry and Biology
2002
Corpus ID: 30880532
2001
2001
Novel entry to the Ergot alkaloids via ring closing metathesis
Katherine L. Lee
,
J. Goh
,
S. Martin
2001
Corpus ID: 94286647
1988
1988
A new antitumor antibiotic, FR-900482: V. Interstrand DNA-DNA cross-links in L1210 cells.
K. Masuda
,
T. Nakamura
,
K. Shimomura
,
T. Shibata
,
H. Terano
,
M. Kohsaka
Journal of antibiotics (Tokyo. )
1988
Corpus ID: 18854654
FR-900482 (Fig. 1) is a new antitumor antibiotic isolated from the culture broth of Streptomyces sandaensis No. 68971~3). It has…
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Highly Cited
1987
Highly Cited
1987
A new antitumor antibiotic, FR-900482. III. Antitumor activity in transplantable experimental tumors.
K. Shimomura
,
O. Hirai
,
+4 authors
H. Kikuchi
Journal of antibiotics (Tokyo. )
1987
Corpus ID: 17243525
FR-900482 (4-formyl-6,9-dihydroxy-14-oxa-1,11-diazatetracyclo[7.4.1.02,7, O10,12]tetradeca-2,4,6-triene-8-ylmethyl carbamate), a…
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1987
1987
A NEW ANTITUMOR ANTIBIOTIC, FR-900482
O. Hirai
,
K. Shimomura
,
T. Mizota
,
S. Matsumoto
,
J. Mori
,
H. Kikuchi
1987
Corpus ID: 76249227
The new antibiotic FR-900482 (4-formyl-6, 9-dihydroxy-14-oxa-l, ll-diazatetracyclo[7.4.1.O2, 7.O10, 12]tetradeca-2, 4, 6-triene-8…
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1987
1987
A new antitumor antibiotic, FR-900482. I. Taxonomic studies on the producing strain: a new species of the genus Streptomyces.
M. Iwami
,
S. Kiyoto
,
H. Terano
,
M. Kohsaka
,
H. Aoki
,
H. Imanaka
Journal of antibiotics (Tokyo. )
1987
Corpus ID: 12309442
A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil…
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