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FR 900482

Known as: 3,9-Epoxy-3H-azirino(2,3-c)(1)benzazocine-5-carboxaldehyde, 8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,9,9a-hexahydro-7,9-dihydroxy-, FR-900482, FR900482 
National Institutes of Health

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Broader (1)

Oxazines

Papers overview

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2011
2011
Development of a flexible strategy towards FR900482 and the mitomycins.
FR900482 and the mitomycins are two intriguing classes of alkaloid natural products that have analogous biological mechanisms and… 
2009
2009
Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C.
Beyond the identification of 3-amino-5-hydroxybenzoic acid (AHBA) and D-glucosamine as biosynthetic precursors to mitomycin C (5… 
2007
2007
Synthetic and biosynthetic studies on FR900482 and mitomycin C: an efficient and stereoselective hydroxymethylation of an advanced benzazocane intermediate.
We report a simple, efficient, and stereoselective Mukaiyama aldol approach to install the key hydroxymethyl moiety into the… 
2003
2003
Formal enantiospecific synthesis of (+)-FR900482.
The enantiospecific synthesis of FK973, and thus a formal enantiospecific synthesis of the antitumor antibiotic (+)-FR900482, is… 
2002
2002
Differential effects of FR900482 and FK317 on apoptosis, IL-2 gene expression, and induction of vascular leak syndrome.
2001
2001
Novel entry to the Ergot alkaloids via ring closing metathesis
1988
1988
A new antitumor antibiotic, FR-900482: V. Interstrand DNA-DNA cross-links in L1210 cells.
FR-900482 (Fig. 1) is a new antitumor antibiotic isolated from the culture broth of Streptomyces sandaensis No. 68971~3). It has… 
Highly Cited
1987
Highly Cited
1987
A new antitumor antibiotic, FR-900482. III. Antitumor activity in transplantable experimental tumors.
FR-900482 (4-formyl-6,9-dihydroxy-14-oxa-1,11-diazatetracyclo[7.4.1.02,7, O10,12]tetradeca-2,4,6-triene-8-ylmethyl carbamate), a… 
1987
1987
A NEW ANTITUMOR ANTIBIOTIC, FR-900482
The new antibiotic FR-900482 (4-formyl-6, 9-dihydroxy-14-oxa-l, ll-diazatetracyclo[7.4.1.O2, 7.O10, 12]tetradeca-2, 4, 6-triene-8… 
1987
1987
A new antitumor antibiotic, FR-900482. I. Taxonomic studies on the producing strain: a new species of the genus Streptomyces.
A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil… 
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