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FOXO4 wt Allele

Known as: Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 7 Gene, ALL1-Fused Gene from X Chromosome, MGC120490 
Human FOXO4 wild-type allele is located in the vicinity of Xq13.1 and is approximately 7 kb in length. This allele, which encodes forkhead box… 
National Institutes of Health

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9 relations
AKT Signaling PathwayFOXO4 geneForkhead Box Protein O4Homo sapiens

Papers overview

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Highly Cited
2014
Highly Cited
2014
Maternal obesity is associated with a lipotoxic placental environment.
Highly Cited
2013
Highly Cited
2013
Regulation of FOXOs and p53 by SIRT1 Modulators under Oxidative Stress
Excessive reactive oxygen species (ROS) induce apoptosis and are associated with various diseases and with aging. SIRT1 (sirtuin… 
Review
2011
Review
2011
Forkhead homeobox type O transcription factors in the responses to oxidative stress.
Reactive oxygen species (ROS) and cellular oxidative stress are involved in many physiological and pathophysiological processes… 
Highly Cited
2008
Highly Cited
2008
Distinct roles for Foxo1 at multiple stages of B cell differentiation
The transcription factors Foxo1, Foxo3 and Foxo4 modulate cell fate 'decisions' in diverse systems. Here we show that Foxo1… 
Highly Cited
2005
Highly Cited
2005
FOXO‐dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells
Endothelial progenitor cells (EPCs) contribute to postnatal neovascularization. Risk factors for coronary artery disease reduce… 
Review
2004
Review
2004
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation.
FoxO (forkhead box O; forkhead members of the O class) are transcription factors that function under the control of insulin… 
Highly Cited
2003
Highly Cited
2003
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells.
Highly Cited
2002
Highly Cited
2002
The Forkhead Transcription Factor AFX Activates Apoptosis by Induction of the BCL-6 Transcriptional Repressor*
The activation of the AKT/protein kinase B kinases by mutation of the PTEN lipid phosphatase results in enhanced survival of a… 
Highly Cited
2000
Highly Cited
2000
Increased AKT Activity Contributes to Prostate Cancer Progression by Dramatically Accelerating Prostate Tumor Growth and Diminishing p27Kip1 Expression*
The PTEN tumor suppressor gene is frequently inactivated in human prostate cancers, particularly in more advanced cancers… 
Highly Cited
1999
Highly Cited
1999
Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B.
The regulation of intracellular localization of AFX, a human Forkhead transcription factor, was studied. AFX was recovered as a… 
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