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FOLFOX Regimen

Known as: CF/5-FU/L-OHP, FOLFOX, Fluorouracil/Leucovorin Calcium/Oxaliplatin 
An abbreviation for a chemotherapy combination used to treat colorectal cancer that is advanced or has come back. It is also being studied in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
PURPOSE The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin in the Adjuvant Treatment of Colon… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND The Panitumumab Randomized trial In combination with chemotherapy for Metastatic colorectal cancer to determine… Expand
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Highly Cited
2012
Highly Cited
2012
Although microRNA-21 (miR-21) is emerging as an oncogene and has been shown to target several tumor suppressor genes, including… Expand
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Highly Cited
2012
Highly Cited
2012
Purpose: The purpose of this study was to examine the prognostic and oxaliplatin predictive value of mismatch repair (MMR) status… Expand
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Highly Cited
2010
Highly Cited
2010
BackgroundThe optimal duration, safety, and benefit of preoperative chemotherapy in patients with colorectal liver metastases… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Bevacizumab significantly improves survival when added to chemotherapy for metastatic colorectal cancer (mCRC). The… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE This study compared chemotherapy discontinuation with maintenance therapy with leucovorin and fluorouracil after six… Expand
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Highly Cited
2008
Highly Cited
2008
4000 Background: Efficacy analyses of the randomized phase II OPUS trial have previously failed to show significant improvements… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE Liver metastases represent the principal cause of death in patients with advanced colorectal cancer (CRC). Injection of… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE Three agents with differing mechanisms of action are available for treatment of advanced colorectal cancer: fluorouracil… Expand
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