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Leucovorin Calcium

Known as: Leucovorin, Calcium, CF, L-CF 
An active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
BACKGROUND Irinotecan is active against colorectal cancer in patients whose disease is refractory to fluorouracil. We… Expand
Review
1994
Review
1994
The folic acid antagonist methotrexate (n-10-methyl-aminopterin) is useful in low doses (2.5 to 20 mg/wk) for treating chronic… Expand
Highly Cited
1991
Highly Cited
1991
In an ongoing clinical trial, 100 patients with an unruptured ectopic pregnancy of 3.5 cm or less in greatest dimension were… Expand
Highly Cited
1982
Highly Cited
1982
Since June 1978, 57 patients with primary osteogenic sarcoma of an extremity were treated with high‐dose methotrexate (HDMTX) and… Expand
Highly Cited
1979
Highly Cited
1979
From 1973–1975, 31 patients with biopsied primary osteogenic sarcoma were treated with preoperative chemotherapy followed by… Expand
Review
1978
Review
1978
SummaryThe absorption of methotrexate following intramuscular injection and oral administration of small doses (>30mg/m2) is… Expand
Highly Cited
1976
Highly Cited
1976
In an attempt to shrink primary osteogenic sarcoma and allow complete surgical removal of the primary tumor, without amputating… Expand
Highly Cited
1974
Highly Cited
1974
Abstract Twenty consecutive patients with osteogenic sarcoma without visible metastases received adjuvant chemotherapy starting… Expand
Highly Cited
1972
Highly Cited
1972
High doses of methotrexate with citrovorum factor were administered to 10 patients with metastatic osteogenic sarcoma. A complete… Expand