oxaliplatin

Known as: 1,2-diaminocyclohexane platinum oxalate, oxaliplatinum, trans-l diaminocyclohexane oxalatoplatinum 
An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a 'leaving group… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
n engl j med 362;9 nejm.org march 4, 2010 858 The authors reply: We agree with Hancock that the electrocardiogram presented in… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE Three-year disease-free survival (DFS) was significantly improved in patients who had undergone resection with curative… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE This randomized study assessed whether the best overall response rate (ORR) of cetuximab combined with oxaliplatin… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To evaluate the efficacy and safety of bevacizumab when added to first-line oxaliplatin-based chemotherapy (either… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To determine whether adding cetuximab to irinotecan prolongs survival in patients with metastatic colorectal cancer (mCRC… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Colorectal cancer is the second leading cause of cancer mortality in the United States. Antiangiogenic therapy with… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin (FL). Oxaliplatin improves the… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE Three agents with differing mechanisms of action are available for treatment of advanced colorectal cancer: fluorouracil… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND In advanced metastatic colorectal adenocarcinoma, the addition of a neo-adjuvant systemic treatment to surgery might… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE In a previous study of treatment for advanced colorectal cancer, the LV5FU2 regimen, comprising leucovorin (LV) plus… (More)
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