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oxaliplatin

Known as: 1,2-diaminocyclohexane platinum oxalate, oxaliplatinum, trans-l diaminocyclohexane oxalatoplatinum 
An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a 'leaving group… 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Highly Cited
2010
Highly Cited
2010
Both the pre-apoptotic exposure of calreticulin (CRT) and the post-apoptotic release of high-mobility group box 1 protein (HMGB1… 
Highly Cited
2009
Highly Cited
2009
PURPOSE This randomized study assessed whether the best overall response rate (ORR) of cetuximab combined with oxaliplatin… 
Highly Cited
2008
Highly Cited
2008
PURPOSE To evaluate the efficacy and safety of bevacizumab when added to first-line oxaliplatin-based chemotherapy (either… 
Highly Cited
2008
Highly Cited
2008
BACKGROUND We evaluated capecitabine (an oral fluoropyrimidine) and oxaliplatin (a platinum compound) as alternatives to infused… 
Highly Cited
2007
Highly Cited
2007
PURPOSE Colorectal cancer is the second leading cause of cancer mortality in the United States. Antiangiogenic therapy with… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin (FL). Oxaliplatin improves the… 
Highly Cited
2004
Highly Cited
2004
PURPOSE Three agents with differing mechanisms of action are available for treatment of advanced colorectal cancer: fluorouracil… 
Highly Cited
2000
Highly Cited
2000
PURPOSE In a previous study of treatment for advanced colorectal cancer, the LV5FU2 regimen, comprising leucovorin (LV) plus… 
Review
2000
Review
2000
PURPOSE To study how adding oxaliplatin (l-OHP) to chronomodulated fluorouracil (5-FU)-leucovorin (LV) affected the objective…