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oxaliplatin

Known as: 1,2-diaminocyclohexane platinum oxalate, oxaliplatinum, trans-l diaminocyclohexane oxalatoplatinum 
An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a 'leaving group… 
National Institutes of Health

Related topics

Related topics

33 relations
10 ML oxaliplatin 5 MG/ML Injection10 ML oxaliplatin 5 MG/ML Injection [Eloxatin]ApoptosisCAPOX Regimen

Narrower (2)

ACT 078Eloxatin

Broader (2)

Antineoplastic AgentsOrganoplatinum Compounds

Papers overview

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Highly Cited
2014
Highly Cited
2014
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial.
Highly Cited
2008
Highly Cited
2008
Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer.
PURPOSE Patients with colorectal cancer (CRC) and liver metastases have a poor prognosis, but can benefit from perioperative… 
Highly Cited
2007
Highly Cited
2007
Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin‐based chemotherapy for colorectal liver metastases
The current study evaluated the effect of bevacizumab added to fluoropyrimidine‐plus‐oxaliplatin (5FU/OX) chemotherapy for… 
Highly Cited
2006
Highly Cited
2006
Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases.
PURPOSE Preoperative chemotherapy for colorectal liver metastases (CLM) can produce histologic changes in the nontumor-bearing… 
Highly Cited
2006
Highly Cited
2006
Contribution of the Major Copper Influx Transporter CTR1 to the Cellular Accumulation of Cisplatin, Carboplatin, and Oxaliplatin
The goal of this study was to determine the ability of the major copper influx transporter CTR1 to mediate the cellular… 
Review
2006
Review
2006
The Discovery and Development of Cisplatin
Cisplatin is currently one of the most widely used anticancer drugs in the world. The unlikely events surrounding the discovery… 
Highly Cited
2004
Highly Cited
2004
Oxaliplatin‐induced neurotoxicity: Acute hyperexcitability and chronic neuropathy
Oxaliplatin, a platinum‐based chemotherapeutic agent, is effective in the treatment of solid tumors, particularly colorectal… 
Highly Cited
2004
Highly Cited
2004
Gemcitabine combined with oxaliplatin (GEMOX) in advanced biliary tract adenocarcinoma: a GERCOR study.
BACKGROUND Since gemcitabine-oxaliplatin (GEMOX) has been used in pancreatic adenocarcinoma, we studied its activity and… 
Highly Cited
2001
Highly Cited
2001
A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels.
Oxaliplatin, a new widely used anticancer drug, displays frequent, sometimes severe, acute sensory neurotoxicity accompanied by… 
Review
1998
Review
1998
Oxaliplatin: a review of preclinical and clinical studies.
Of the new generation platinum compounds that have been evaluated, those with the 1,2-diaminocyclohexane carrier ligand-including… 
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